Magnesium sulfate
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See critical care quick reference for drug doses by weight.
General
- Type: Antiarrhythmics
- Dosage Forms:
- Common Trade Names:
Adult Dosing
- Loading dose = 1-2gm in 10mL D5W over 1-2min (cardiac arrest)
- Loading dose = 1-4gm in 50-100 D5W over 20-60min (spontaneous circulation)
Indications
- Torsades
- Refractory v-tach/fib (regardless of Mg level)
Pediatric Dosing
Cardiac
- 25-50 mg/kg IV x 1
See critical care quick reference for drug doses by weight.
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Hypotension (rare)
Common
Pharmacology
- Half-life:
- Onset of action = Immediate
- Duration of action = 30min
- Metabolism:
- Excretion:
Mechanism of Action
- Increases vasomotor tone
- Prolongs AV conduction; prolongs refractoriness