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- Negative Pressure Pulmonary Edema
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- Negative-pressure pulmonary edema (NPPE) occurs after a patient makes strong inspiratory effort against a blocked airway. The negative pressure causes hydrostatic edema that can be life-threatening if not but minimized if treated early, usually resolves after 24-48 hours.
- Patients have and airway obstructive process either from an allergy, laryngospasm, trauma, and commonly in the case of hangings.
- Tetrodotoxin and the Blue Ringed Octopus
Tetrodotoxin is from the pufferfish, blue octopus and some poisonous frogs. Neurotoxicity results from inhibition of Na-K pumps causing paresthesias and rebound hypersensitivity. Like most poisons in toxicology, the treatment is aggressive supportive care.… Read more
- The Current State of Refractory VF
The following guest post is written by MD candidate Joseph N. Ponce at McGovern Medical School, Houston TX, and describes the current state of evidence with adjunctive techniques to treat refractory VF.
Refractory ventricular fibrillation (RVF) is a life-threatening cardiac arrhythmia unresponsive to traditional methods of defibrillation and advanced cardiovascular life support (ACLS). Current literature lacks a uniform definition for RVF, however, some studies provide more specific clinical definitions of refractory ventricular fibrillation such as ventricular fibrillation that is resistant to at least three defibrillation attempts, 300 mg of amiodarone, and does not exhibit return of spontaneous circulation (ROSC) after > 10 min of cardiopulmonary resuscitation (CPR).… Read more