Difference between revisions of "Oxacillin"
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==Pediatric Dosing== | ==Pediatric Dosing== | ||
| + | ===General=== | ||
| + | *Mild-to-moderate infection | ||
| + | **50 mg/kg/day IM/IV divided q6 hours | ||
| + | **First Dose: 12.5 mg/kg IM/IV x 1 | ||
| + | **Maximum: 4 g/day | ||
| + | *Severe infection | ||
| + | **100 mg/kg/day IM/IV divided q4-6 hours | ||
| + | **16.6-25 mg/kg IM/IV x 1 | ||
| + | **Max: 12 g/day | ||
| + | |||
| + | ===Community-Acquired [[Pneumonia]] (>3 Months)<ref>IDSA/PIDS, 2011</ref>=== | ||
| + | *150-200 mg/kg/day divided q6-8 hours | ||
| + | *First Dose: 37.5-66.6 mg/kg IV x 1 | ||
| + | *For [[MSSA]] | ||
==Special Populations== | ==Special Populations== | ||
Revision as of 18:54, 6 April 2014
Contents
General
- Type: Anti-Staphylococcal Penicillin
- Dosage Forms:
- Common Trade Names:
Adult Dosing
General
- Mild-to-moderate infection
- 250-500 mg IM/IV q4-6 hours
- Severe infection
- 1g IM/IV q4-6 hours
Endocarditis
- 2g IV q4 hours + gentamicin
Prosthetic Joint Infection
- 2g IV q4 hours + rifampin
MSSA
- 2g IV q4 hours
- Examples: brain abscess, bursitis, erysipelas, mastitis, mastoiditis, osteomyelitis, perinephric abscess, pneumonia, pyomyositis, Scalded Skin Syndrome, Toxic Shock Syndrome
Pediatric Dosing
General
- Mild-to-moderate infection
- 50 mg/kg/day IM/IV divided q6 hours
- First Dose: 12.5 mg/kg IM/IV x 1
- Maximum: 4 g/day
- Severe infection
- 100 mg/kg/day IM/IV divided q4-6 hours
- 16.6-25 mg/kg IM/IV x 1
- Max: 12 g/day
Community-Acquired Pneumonia (>3 Months)[1]
- 150-200 mg/kg/day divided q6-8 hours
- First Dose: 37.5-66.6 mg/kg IV x 1
- For MSSA
Special Populations
- Pregnancy Rating:
- Lactation:
- Renal Dosing
- Adult
- Pediatric
- Hepatic Dosing
- Adult
- Pediatric
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
Common
Pharmacology
- Half-life:
- Metabolism:
- Excretion:
- Mechanism of Action:
See Also
Source
- ↑ IDSA/PIDS, 2011