Oxacillin

Revision as of 19:31, 6 April 2014 by Rossdonaldson1 (talk | contribs) (Special Populations)

General

  • Type: Anti-Staphylococcal Penicillin
  • Dosage Forms: IM; IV
  • Common Trade Names:

Adult Dosing

General

  • Mild-to-moderate infection
    • 250-500 mg IM/IV q4-6 hours
  • Severe infection
    • 1g IM/IV q4-6 hours

Endocarditis

Prosthetic Joint Infection

MSSA

Pediatric Dosing

General

  • Mild-to-moderate
    • 50 mg/kg/day IM/IV divided q6 hours
    • First Dose: 12.5 mg/kg IM/IV x 1
    • Max: 4 g/day
  • Severe
    • 100 mg/kg/day IM/IV divided q4-6 hours
    • First Dose: 16.6-25 mg/kg IM/IV x 1
    • Max: 12 g/day

Community-Acquired Pneumonia (>3 Months)[1]

  • 150-200 mg/kg/day divided q6-8 hours
  • First Dose: 37.5-66.6 mg/kg IV x 1
  • For MSSA

Special Populations

  • Pregnancy Rating: B
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Source

  1. IDSA/PIDS, 2011