Oxygen toxicity: Difference between revisions

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==Clinical Features==
==Clinical Features==
=== Central nervous system ===
===Pulmonary===
*Tracheobronchial irritation → pleuritic chest pain, dyspnea and coughing<ref name="Thomson">Thomson L, Paton J. Oxygen toxicity. Paediatr Respir Rev. 2014 Jun;15(2):120-3.</ref>
*Atelectasis
*Diffuse alveolar damage → [[Pulmonary edema]]/[[ARDS]]
 
===Central nervous system===
*Tunnel vision
*Tunnel vision
*Tinnitus
*Tinnitus
*[[Nausea]]
*[[Nausea]]
*Twitching (especially of the face)
*Facial twitching
*Irritability (personality changes, [[anxiety]], confusion, etc.)
*Irritability (personality changes, anxiety, confusion, etc.)
*[[Dizziness]]
*[[Seizure]]
*Tonic–clonic [[seizure]]
 
=== Pulmonary Toxicity ===
*Frequent coughing leading to [[pulmonary edema]]/[[ARDS]]


=== Ocular Toxicity===
===Ocular===
*Retinopathy of prematurity
*Generally only seen in infants
**Retinopathy of prematurity (retrolentar fibroplasia)
*In adults exposed to repeated toxic levels of oxygen, can get hyperoxic myopia, which resolves spontaneously<ref>Anderson B, Farmer JC. Hyperoxic myopia. Transactions of the American Ophthalmological Society. 1978;76:116-124.</ref>


==Differential Diagnosis==
==Differential Diagnosis==
{{Scuba diving DDX}}
{{Scuba diving DDX}}


==Workup==
==Diagnosis==
*Clinical diagnosis


==Management==
==Management==
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==Disposition==
==Disposition==
*Admit


==See Also==
==See Also==
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==External Links==
==External Links==


==Sources==
==References==
<references/>
<references/>


[[Category:Environ]]
[[Category:Environ]]

Revision as of 07:40, 4 March 2016

Background

  • Resulting from the harmful effects of breathing oxygen at elevated partial pressures

Clinical Features

Pulmonary

  • Tracheobronchial irritation → pleuritic chest pain, dyspnea and coughing[1]
  • Atelectasis
  • Diffuse alveolar damage → Pulmonary edema/ARDS

Central nervous system

  • Tunnel vision
  • Tinnitus
  • Nausea
  • Facial twitching
  • Irritability (personality changes, anxiety, confusion, etc.)
  • Seizure

Ocular

  • Generally only seen in infants
    • Retinopathy of prematurity (retrolentar fibroplasia)
  • In adults exposed to repeated toxic levels of oxygen, can get hyperoxic myopia, which resolves spontaneously[2]

Differential Diagnosis

Diving Emergencies

Diagnosis

  • Clinical diagnosis

Management

  • Removal from high partial pressure of oxygen, if possible

Disposition

  • Admit

See Also

External Links

References

  1. Thomson L, Paton J. Oxygen toxicity. Paediatr Respir Rev. 2014 Jun;15(2):120-3.
  2. Anderson B, Farmer JC. Hyperoxic myopia. Transactions of the American Ophthalmological Society. 1978;76:116-124.