Difference between revisions of "Penicillin G Procaine"

(General)
(Adult Dosing)
Line 5: Line 5:
  
 
==Adult Dosing==
 
==Adult Dosing==
 +
===[[Anthrax]]===
 +
*Inhalational (Postexposure Prophylaxis)
 +
**1,200,000 units IM q12 hours x 60 days (see below)
 +
**Info: Total treatment duration = 60 days. Do not give IM for over 2 weeks, switching alternative treatment to complete course
 +
*Cutaneous, Nonsevere (Treatment)
 +
**600,000-1,200,000 units/day IM
 +
 +
===[[Endocarditis]] by susceptible [[Streptococcus viridans]]===
 +
*1.2 million units IM q6 hours x 2-4 weeks + [[aminoglycoside]]
 +
 +
===Neurosyphilis===
 +
*2.4 million units/day IM + 500 mg probenecid PO QID x 10-14 days
 +
*Info: [[Penicillin G]] aqueous I.V. is preferred
 +
 +
===Whipple's Disease===
 +
*1.2 million units/day + streptomycin x 10-14 days
 +
*Followed by [[trimethoprim/sulfamethoxazole]] or doxycycline x 1 year
  
 
==Pediatric Dosing==
 
==Pediatric Dosing==

Revision as of 21:08, 6 April 2014

General

  • Type: Natural Penicillin
  • Dosage Forms: IM
  • Common Trade Names:

Adult Dosing

Anthrax

  • Inhalational (Postexposure Prophylaxis)
    • 1,200,000 units IM q12 hours x 60 days (see below)
    • Info: Total treatment duration = 60 days. Do not give IM for over 2 weeks, switching alternative treatment to complete course
  • Cutaneous, Nonsevere (Treatment)
    • 600,000-1,200,000 units/day IM

Endocarditis by susceptible Streptococcus viridans

Neurosyphilis

  • 2.4 million units/day IM + 500 mg probenecid PO QID x 10-14 days
  • Info: Penicillin G aqueous I.V. is preferred

Whipple's Disease

Pediatric Dosing

Special Populations

  • Pregnancy:
  • Lactation:
  • Renal Dosing
    • Adult
    • Pediatric
  • Hepatic Dosing
    • Adult
    • Pediatric

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:
  • Mechanism of Action:

See Also

Source