Post-tPA Hemorrhage in CVA

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Consider bleeding if decreased LOC, increased weakness, new headache, sudden rise in blood pressure


If bleeding occurs after tPA:

  • Stop tpa infusion
  • Stat head CT
  • if no bleeding resume tpa
  • If bleeding check labs, consider fibrinogen replacement
  • Recheck pt/ptt, platelets, fibrinogen levels
  • Prepare 6- 8 units cryoprecipitate
  • Prepare 6- 8 units platelets


6/06 MISTRY