Difference between revisions of "Posterior reversible encephalopathy syndrome"

(Background)
 
Line 2: Line 2:
 
*Abbreviation: PRES
 
*Abbreviation: PRES
 
*Risk factors include: [[malignant hypertension]], immunosuppression, [[eclampsia]]
 
*Risk factors include: [[malignant hypertension]], immunosuppression, [[eclampsia]]
 +
*Poorly understood entity, but thought to be due to failure of cerebral auto-regulation in which the brain sees too high of systemic pressures leading to vasogenic edema
 +
*Somewhat of a misnomer as changes seen on MRI are not limited to the posterior fossa and symptoms are not always reversible
 +
**Renamed reversible posterior leukoencephalopathy syndrome (RPLS) by the American Academy of Neurology.
  
 
[[File:Posterior reversible encephalopathy syndrome MRI.jpg|thumb|Magnetic resonance image showing multiple cortico-subcortical areas of hyperdense signal involving the occipital and parietal lobes bilaterally and pons in a patient with posterior reversible encephalopathy syndrome]]
 
[[File:Posterior reversible encephalopathy syndrome MRI.jpg|thumb|Magnetic resonance image showing multiple cortico-subcortical areas of hyperdense signal involving the occipital and parietal lobes bilaterally and pons in a patient with posterior reversible encephalopathy syndrome]]

Latest revision as of 17:49, 13 February 2020

Background

  • Abbreviation: PRES
  • Risk factors include: malignant hypertension, immunosuppression, eclampsia
  • Poorly understood entity, but thought to be due to failure of cerebral auto-regulation in which the brain sees too high of systemic pressures leading to vasogenic edema
  • Somewhat of a misnomer as changes seen on MRI are not limited to the posterior fossa and symptoms are not always reversible
    • Renamed reversible posterior leukoencephalopathy syndrome (RPLS) by the American Academy of Neurology.
Magnetic resonance image showing multiple cortico-subcortical areas of hyperdense signal involving the occipital and parietal lobes bilaterally and pons in a patient with posterior reversible encephalopathy syndrome

Clinical Features[1]

Differential Diagnosis[2]

Seizure

Evaluation

Management

Disposition

  • Admit

See Also

References

  1. Staykov D. "Posterior reversible encephalopathy syndrome". PMID 21257628
  2. 2.0 2.1 Garg RK (January 2001). "Posterior leukoencephalopathy syndrome". Postgrad Med J 77 (903): 24–8. doi:10.1136/pmj.77.903.24. PMC 1741870. PMID 11123390