Revision as of 05:57, 13 January 2017 by Mackeym2 (talk | contribs)


  • Preventable condition in infants and children that is attributed to Vitamin D deficiency and Hypocalcemia
  • Extreme deficiency leading to decrease bone mineralization in children, with or without hypocalcemia
  • Risk factors for Vitamin D deficiency in infants include:
    • Exclusive breastfed infants without vitamin D supplementation
    • Dark skin pigmentation
    • Maternal Vitamin D deficiency
      • In utero, 25-hydroxyvitamin D passes through the placenta to the infant

Clinical Features

  • Peak incidence between 3 and 18 months of age
  • Enlarged skull, joints of long bones, and rib cage
  • Curvature of the spine and femurs
  • Generalized muscle weakness

Differential Diagnosis



  • Prevention key:
    • For healthy infants, children, and adolescents recommend a vitamin D intake of at least 400 IU/day


See Also

External Links