Difference between revisions of "SSRI toxicity"

(Text replacement - "==Treatment==" to "==Management==")
(Clinical Features)
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*QRS, [[QT prolongation]] (citalopram only)
*QRS, [[QT prolongation]] (citalopram only)
*[[Serotonin syndrome]]
*[[Serotonin syndrome]]
*Coma and seizures (rare)
==Differential Diagnosis==
==Differential Diagnosis==

Revision as of 14:18, 1 September 2019


  • Most serious adverse effect is potential to produce Serotonin Syndrome
  • Fatalities are uncommon with pure overdoses

Clinical Features

Differential Diagnosis

Anticholinergic toxicity Causes


  • GI decontamination
    • Activated charcoal x1
    • Gastric lavage unnecessary


  • Consider admission for patients who are tachycardic or lethargic 6hr after ingesion

See Also


  1. Dawson AH, Buckley NA. Pharmacological management of anticholinergic delirium – theory, evidence and practice. Br J Clin Pharmacol. 2015;81(3):516-24.