SSRI toxicity

Revision as of 03:21, 16 December 2014 by Rossdonaldson1 (talk | contribs)

Background

  • Most serious adverse effect is potential to produce Serotonin Syndrome
  • Fatalities are uncommon with pure overdoses

Clinical Features

  • N/V
  • Sedation
  • Tremor
  • Sinus Tachycardia
  • QRS, QT prolongation (citalopram only)
  • Serotonin Syndrome

Treatment

  • GI decontamination
    • Activated charcoal x1
    • Gastric lavage unnecessary

Disposition

  • Consider admission for patients who are tachycardic or lethargic 6hr after ingesion

See Also

Source

Tintinalli