SSRI toxicity

Revision as of 05:54, 9 July 2016 by Neil.m.young (talk | contribs) (Text replacement - "==Treatment==" to "==Management==")


  • Most serious adverse effect is potential to produce Serotonin Syndrome
  • Fatalities are uncommon with pure overdoses

Clinical Features

Differential Diagnosis

Anticholinergic toxicity Causes


  • GI decontamination
    • Activated charcoal x1
    • Gastric lavage unnecessary


  • Consider admission for patients who are tachycardic or lethargic 6hr after ingesion

See Also


  1. Dawson AH, Buckley NA. Pharmacological management of anticholinergic delirium – theory, evidence and practice. Br J Clin Pharmacol. 2015;81(3):516-24.