Selective serotonin reuptake inhibitor toxicity: Difference between revisions
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==Background== | |||
*Most serious adverse effect is potential to produce [[Serotonin Syndrome]] | |||
*Fatalities are uncommon with pure overdoses | |||
==Clinical Features== | |||
*N/V | |||
*Sedation | |||
*Tremor | |||
*Sinus Tachycardia | |||
*QRS, QT prolongation (citalopram only) | |||
*[[Serotonin Syndrome]] | |||
==Treatment== | |||
*GI decontamination | |||
**Activated charcoal x1 | |||
**Gastric lavage unnecessary | |||
==Disposition== | |||
*Consider admission for patients who are tachycardic or lethargic 6hr after ingesion | |||
==See Also== | |||
*[[Serotonin syndrome]] | |||
*[[SNRI Toxicity]] | |||
==Source== | |||
Tintinalli | |||
[[Category:Tox]] | |||
Revision as of 03:21, 16 December 2014
Background
- Most serious adverse effect is potential to produce Serotonin Syndrome
- Fatalities are uncommon with pure overdoses
Clinical Features
- N/V
- Sedation
- Tremor
- Sinus Tachycardia
- QRS, QT prolongation (citalopram only)
- Serotonin Syndrome
Treatment
- GI decontamination
- Activated charcoal x1
- Gastric lavage unnecessary
Disposition
- Consider admission for patients who are tachycardic or lethargic 6hr after ingesion
See Also
Source
Tintinalli