Sgarbossa's criteria: Difference between revisions

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==Background==
==Background==
*Assesses likelihood that pt w/ chest pain and baseline LBBB has myocardial damage (+CK-MB)  
*Assesses likelihood that patient with chest pain and baseline [[LBBB]] has myocardial damage. Developed in 1996 by Elena Sgarbossa <ref>Sgarbossa EB, Pinski SL, Barbagelata MD, et al. Electrocardiographic Diagnosis of Evolving Acute Myocardial Infarction in the Presence of Left Bundle-Branch Block. NEJM. 1996;334(8)</ref>
**Criteria also applies to LBBB due to paced rhythm
**Criteria also applies to [[LBBB]] due to ventricularly paced rhythm, with more recent reviews demonstrating ~98% specificity when QRS amplitude taken into consideration <ref>Maloy KR, Bhat R, Davis J, et al. Sgarbossa Criteria are highly specific for acute myocardial infarction with pacemakers. West J Emerg Med. 2010;11(4):354-357. (Retrospective cohort; 57 patients)</ref> <ref>Madias JE. The nonspecificity of ST-segment elevation > or =5.0 mm in V1-V3 in the diagnosis of acute myocardial infarction in the presence of ventricular paced rhythm. J Electrocardiol 2004 Apr; 37(2) 135-9.</ref>
*Low Sn, High Sp
*Original Criteria had low sensitivity(20%), high specificity (98%)
**Still consider PCI/t-PA for pts w/ LBBB and "good story" despite not meeting the criteria
**Two main issues suggested for low sensitivity of original rule. First, use of CK (with or without MB) for diagnosis of acute MI, not angiography. Therefore both STEMI & NSTEMI included in acute MI group. Second, anterior STEMI diagnosis limited by criteria absolute 5mm ST elevation<ref>Smith SW, Dodd KW, Henry TD et al. Diagnosis of ST-Elevation Myocardial Infarction in the Presence of Left Bundle Branch Block with the ST-Elevation to S-Wave Ratio in a Modified Sgarbossa Rule. Annals of Emerg Med 2012;60(6)</ref>
**Still consider PCI/t-PA for patients with LBBB and "good story" despite not meeting the criteria
*Previously, a new or presumably new LBBB was indication for emergent reperfusion therapy (i.e. STEMI equivalent) 
**Guidelines were changed in 2013 due to a high number of false positives
**LBBB should now be taken into consideration, but no longer indication for emergent cardiac catheterization<ref>Cai et al. The left bundle-branch block puzzle in the 2013 ST-elevation myocardial infarction guideline: from fasely declaring emergnecy to denying reperfusion in a high-risk population. Are the Sgarbossa Criteria ready for prime time?. Am Heart J 2013 Sep; 166(3) 409-413. </ref>
*Subsequent Smith Modification improves sensitivity (91%) for a slightly lower specificity (90%), and was validated by Meyers et al in 2015<ref>Meyers HP, Limkakeng AT, Jaffa EJ et al. Validation of the modified Sgarbossa criteria for acute coronary occlusion in the setting of left bundle branch block: A retrospective case-control study. Am Heart J. 2015;170(6)1255-64.</ref>


==Criteria==
==Criteria==
*ST elevation ≥1 mm in a lead with upward (concordant) QRS complex - 5 points
{{Sgarbossa Criteria}}
*ST depression ≥1 mm in lead V1, V2, or V3 - 3 points
[[File:Sgarbossa - all three.jpg|thumbnail|Sgarbossa original criteria]]
*ST elevation ≥5 mm in a lead with downward (discordant) QRS complex - 2 points
*(See [[#Example | below]] for example of all 3 criteria)


*Smith's modification of the third rule of the Sgarbossa criteria to ST depression or elevation discordant with the QRS complex and with a magnitude of at least 25% of that of the QRS complex increases sensitivity from 52% to 91% at the expense of reducing specificity from 98% to 90%.
==Management==
*Discussion with a cardiologist should precede activation of the Cath Lab for any of the Sgarbossa or modified Sgarbossa criteria


==Points==
==See Also==
*≥3 points = 98% probability of [[STEMI]]
*[[EBQ:Sgarbossa Criteria Study]]
*[[ST-Elevation Myocardial Infarction (STEMI)]]
*[[EBQ:Sgarbossa Criteria Study|Original Study - Sgarbossa Criteria for MI in LBBB]]


==Example==
==External Links==
[[File:Sgarbossa.jpg]]
*http://lifeinthefastlane.com/ecg-library/basics/sgarbossa/
 
*http://emcrit.org/podcasts/left-bundle-branch-block/
==See Also==
[[ST-Elevation Myocardial Infarction (STEMI)]]


==Source==
==Video==
*Sgarbossa, American Heart Journal 2006
{{#widget:YouTube|id=VX2HF3xIodQ}}
*Sgarbossa, NEJM, February, 1996


[[Category:Cards]]
==References==
<references/>
[[Category:Cardiology]]

Latest revision as of 18:54, 8 March 2021

Background

  • Assesses likelihood that patient with chest pain and baseline LBBB has myocardial damage. Developed in 1996 by Elena Sgarbossa [1]
    • Criteria also applies to LBBB due to ventricularly paced rhythm, with more recent reviews demonstrating ~98% specificity when QRS amplitude taken into consideration [2] [3]
  • Original Criteria had low sensitivity(20%), high specificity (98%)
    • Two main issues suggested for low sensitivity of original rule. First, use of CK (with or without MB) for diagnosis of acute MI, not angiography. Therefore both STEMI & NSTEMI included in acute MI group. Second, anterior STEMI diagnosis limited by criteria absolute 5mm ST elevation[4]
    • Still consider PCI/t-PA for patients with LBBB and "good story" despite not meeting the criteria
  • Previously, a new or presumably new LBBB was indication for emergent reperfusion therapy (i.e. STEMI equivalent)
    • Guidelines were changed in 2013 due to a high number of false positives
    • LBBB should now be taken into consideration, but no longer indication for emergent cardiac catheterization[5]
  • Subsequent Smith Modification improves sensitivity (91%) for a slightly lower specificity (90%), and was validated by Meyers et al in 2015[6]

Criteria

Original Criteria

Sgarbossa's Original Criteria

≥3 points = 98% probability of STEMI[7]

  • ST elevation ≥1 mm in a lead with upward QRS complex (concordant) - 5 points
  • ST depression ≥1 mm in lead V1, V2, or V3 - 3 points
  • ST elevation ≥5 mm in a lead with downward QRS complex (discordant) - 2 points

Smith's modification[8]

Smith's Modified Sgarbossa 3rd Rule
  • Changes the 3rd rule of original Sgarbossa's Criteria to be ST depression OR elevation discordant with the QRS complex and with a magnitude of at least 25% of the QRS
    • Increases Sn from 52% → 91% at the expense of reducing Sp from 98% → 90%
Sgarbossa original criteria

Management

  • Discussion with a cardiologist should precede activation of the Cath Lab for any of the Sgarbossa or modified Sgarbossa criteria

See Also

External Links

Video

{{#widget:YouTube|id=VX2HF3xIodQ}}

References

  1. Sgarbossa EB, Pinski SL, Barbagelata MD, et al. Electrocardiographic Diagnosis of Evolving Acute Myocardial Infarction in the Presence of Left Bundle-Branch Block. NEJM. 1996;334(8)
  2. Maloy KR, Bhat R, Davis J, et al. Sgarbossa Criteria are highly specific for acute myocardial infarction with pacemakers. West J Emerg Med. 2010;11(4):354-357. (Retrospective cohort; 57 patients)
  3. Madias JE. The nonspecificity of ST-segment elevation > or =5.0 mm in V1-V3 in the diagnosis of acute myocardial infarction in the presence of ventricular paced rhythm. J Electrocardiol 2004 Apr; 37(2) 135-9.
  4. Smith SW, Dodd KW, Henry TD et al. Diagnosis of ST-Elevation Myocardial Infarction in the Presence of Left Bundle Branch Block with the ST-Elevation to S-Wave Ratio in a Modified Sgarbossa Rule. Annals of Emerg Med 2012;60(6)
  5. Cai et al. The left bundle-branch block puzzle in the 2013 ST-elevation myocardial infarction guideline: from fasely declaring emergnecy to denying reperfusion in a high-risk population. Are the Sgarbossa Criteria ready for prime time?. Am Heart J 2013 Sep; 166(3) 409-413.
  6. Meyers HP, Limkakeng AT, Jaffa EJ et al. Validation of the modified Sgarbossa criteria for acute coronary occlusion in the setting of left bundle branch block: A retrospective case-control study. Am Heart J. 2015;170(6)1255-64.
  7. Sgarbossa E. et al.. "Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators". NEJM. 1996. 334(8):481-7
  8. Smith, S. et al. Diagnosis of ST-Elevation Myocardial Infarction in the Presence of Left Bundle Branch Block With the ST-Elevation to S-Wave Ratio in a Modified Sgarbossa Rule. 60(6). 766-776