Revision as of 23:57, 15 July 2016 by ClaireLewis (talk | contribs) (Management)


  • Also known as "Rose gardener's disease"[1]
  • Caused by the fungus Sporothrix schenckii[2] found on rose thorns
  • Usually affects skin, although other rare forms can affect the lungs, joints, bones, and brain
  • Enters skin through small cuts and abrasions, and inhalation for pulmonary disease
  • Can also be acquired from handling cats with the disease

Clinical Features

Progresses slowly: first symptoms may appear 1 to 12 weeks (average 3 weeks) after the initial exposure to the fungus

Forms and Symptoms

  • Cutaneous or skin
    • Most common form
    • Symptoms include nodular lesions or bumps in the skin, at the point of entry and also along lymph nodes and vessels
      • Lesion starts off small and painless, and ranges in color from pink to purple
      • Left untreated, lesion becomes larger and looks similar to an abscess. More lesions will appear until a chronic ulcer develops
  • Pulmonary sporotrichosis
    • Rare
    • From inhalation of spores
    • Symptoms include productive coughing, nodules and cavitations of the lungs, fibrosis, and hilar lymphadenopathy nodes
    • May become superinfected with pneumonia or tuberculosis
  • Disseminated sporotrichosis
    • May affect joints and bones (osteoarticular sporotrichosis) and or CNS (sporotrichosis meningitis)
    • Symptoms include weight loss, anorexia, and appearance of bony lesions

Differential Diagnosis


Skin and Soft Tissue Infection


Hand Infection

Hand and finger infections


Fungal culture of skin, sputum, synovial fluid, or CSF


  • Antifungal medication
    • Itraconazole
      • Drug of choice (more effective than fluconazole)
    • Fluconazole
      • Fluconazole (for patients who cannot tolerate itraconazole)
    • Amphotericin B IV
      • For disseminated of severe disease
  • Surgery
  • Standard antibiotics
    • Lesions sometimes become superinfected, consider as necessary


  • Normally treated as outpatient

See Also


  1. Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
  2. Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 654–6. ISBN 0-8385-8529-9.