Staphylococcus epidermidis: Difference between revisions
 
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==Background==
==Background==
*Staphylococcus epidermidis is a coagulase-negative [[staphylococcus]], a [[gram-positive]] bacteria


==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2010</ref>==
==[[Antibiotic Sensitivities]]<ref>Sanford Guide to Antimicrobial Therapy 2014</ref>==
{| class="wikitable"
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Organisms'''
| align="center" style="background:#f0f0f0;"|'''Category'''
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''Antibiotic'''
| align="center" style="background:#f0f0f0;"|'''Staph. epidermidis'''
| align="center" style="background:#f0f0f0;"|'''[[Staph. Epidermidis]]'''
|-
|-
| Penicillins||Penicillin G||0
| [[Penicillins]]||[[Penicillin G]]||R
|-
|-
| ||Penicillin V||0
| ||[[Penicillin V]]||R
|-
|-
| Anti-Staphylocccal Penicillins||Methicillin||+
| ||[[Methicillin]]||S
|-
|-
| ||Nafcillin/Oxacillin||+
| ||[[Nafcillin]]/[[Oxacillin]]||S
|-
|-
| ||Cloxacillin/Diclox.||+
| ||[[Cloxacillin]]/[[Diclox.]]||S
|-
|-
| Amino-Penicillins||AMP/Amox||0
| Amino-[[Penicillins]]||[[AMP]]/[[Amox]]||R
|-
|-
| ||Amox/Clav||0
| ||[[Amox-Clav]]||R
|-
|-
| ||AMP-Sulb||0
| ||[[AMP-Sulb]]||R
|-
|-
| Anti-Pseudomonal Penicillins||Ticarcillin||+/-
| Anti-Pseudomonal [[Penicillins]]||[[Ticarcillin]]||I
|-
|-
| ||Ticar-Clav||+/-
| ||[[Ticar-Clav]]||I
|-
|-
| ||Pip-Taxo||+
| ||[[Pip-Tazo]]||S
|-
|-
| [[Carbapenems]]||Piperacillin||0
| ||Piperacillin||R
|-
|-
| ||Doripenem||+
| [[Carbapenems]]||Doripenem||S
|-
|-
| ||Ertapenem||+
| ||[[Ertapenem]]||S
|-
|-
| ||Imipenem||+
| ||[[Imipenem]]||S
|-
|-
| ||Meropenem||+
| ||[[Meropenem]]||S
|-
|-
| ||[[Aztreonam]]||0
| ||[[Aztreonam]]||R
|-
|-
| [[Fluroquinolones]]||[[Ciprofloxacin]]||+
| [[Fluroquinolones]]||[[Ciprofloxacin]]||S
|-
|-
| ||Ofloxacin||+
| ||[[Ofloxacin]]||S
|-
|-
| ||Pefloxacin||+
| ||Pefloxacin||S
|-
|-
| ||[[Levofloxacin]]||+
| ||[[Levofloxacin]]||S
|-
|-
| ||Moxifloxacin||+
| ||[[Moxifloxacin]]||S
|-
|-
| ||Gemifloxacin||+
| ||Gemifloxacin||S
|-
|-
| ||Gatifloxacin||+
| ||Gatifloxacin||S
|-
|-
| 1st G [[Cephalosporin]]||Cefazolin||+/-
| 1st G [[Cephalo]]||Cefazolin||I
|-
|-
| 2nd G. [[Cephalosporin]]||[[Cefotetan]]||+/-
| 2nd G. [[Cephalo]]||[[Cefotetan]]||I
|-
|-
| ||Cefoxitin||+/-
| ||[[Cefoxitin]]||I
|-
|-
| ||Cefuroxime||+/-
| ||[[Cefuroxime]]||I
|-
|-
| 3rd/4th G. [[Cephalosporin]]||[[CefoTAXime]]||+/-
| 3rd/4th G. [[Cephalo]]||[[Cefotaxime]]||I
|-
|-
| ||Cefizoxime||+/-
| ||Cefizoxime||I
|-
|-
| ||[[CefTRIAXone]]||+/-
| ||[[CefTRIAXone]]||I
|-
|-
| ||Ceftobiprole||+
| ||Ceftaroline||S
|-
|-
| ||Ceftaroline||+
| ||[[CefTAZidime]]||I
|-
|-
| ||[[CefTAZidime]]||+/-
| ||[[Cefepime]]||I
|-
|-
| ||[[Cefepime]]||+/-
| Oral 1st G. [[Cephalo]]||Cefadroxil||I
|-
|-
| Oral 1st G.  [[Cephalosporin]]||Cefadroxil||+/-
| ||[[Cephalexin]]||I
|-
|-
| ||[[Cephalexin]]||+/-
| Oral 2nd G. [[Cephalo]]||Cefaclor/Loracarbef||I
|-
|-
| Oral 2nd G.  [[Cephalosporin]]||Cefaclor/Loracarbef||+/-
| ||Cefproxil||I
|-
|-
| ||Cefproxil||+/-
| ||Cefuroxime axetil||I
|-
|-
| ||Cefuroxime axetil||+/-
| Oral 3rd G. [[Cephalo]]||Cefixime||R
|-
|-
| Oral 3rd G.  [[Cephalosporin]]||Cefixime||0
| ||Ceftibuten||R
|-
|-
| ||Ceftibuten||0
| ||Cefpodox/Cefdinir/Cefditoren||I
|-
|-
| ||Cefpodox/Cefdinir/Cefditoren||+/-
| [[Aminoglycosides]]||[[Gentamicin]]||I
|-
|-
| [[Aminoglycosides]]||[[Gentamicin]]||+/-
| ||Tobramycin||I
|-
|-
| ||Tobramycin||+/-
| ||[[Amikacin]]||I
|-
|-
| ||[[Amikacin]]||+/-
| ||[[Chloramphenicol]]||R
|-
|-
| ||Chloramphenicol||0
| ||[[Clindamycin]]||R
|-
|-
| ||[[Clindamycin]]||0
| [[Macrolides]]||Erythromycin||I
|-
|-
| [[Macrolides]]||Erythromycin||+/-
| ||[[Azithromycin]]||R
|-
|-
| ||[[Azithromycin]]||0
| ||Clarithromycin||R
|-
|-
| ||Clarithromycin||0
| Ketolide||Telithromycin||R
|-
|-
| Ketolide||Telithromycin||0
| Tetracyclines||[[Doxycycline]]||R
|-
|-
| Tetracyclines||[[Doxycycline]]||0
| ||Minocycline||R
|-
|-
| ||Minocycline||0
| Glycylcycline||Tigecycline||S
|-
|-
| Glycylcycline||Tigecycline||+
| ||Daptomycin||S
|-
|-
| Glyco/Lipoclycopeptides||[[Vancomycin]]||+
| Glyco/Lipoclycopeptides||[[Vancomycin]]||S
|-
|-
| ||Teicoplanin||+/-
| ||Teicoplanin||I
|-
|-
| ||Telavancin||+
| ||Telavancin||S
|-
|-
| ||Fusidic Acid||+
| ||Fusidic Acid||S
|-
|-
| ||Trimethoprim||+
| ||Trimethoprim||S
|-
|-
| ||[[TMP-SMX]]||+/-
| ||[[TMP-SMX]]||I
|-
|-
| Urinary Agents||[[Nitrofurantoin]]||
| Urinary Agents||[[Nitrofurantoin]]||X1
|-
|-
| ||Fosfomycin||
| ||Fosfomycin||X1
|-
|-
| Other||[[Rifampin]]||+
| Other||[[Rifampin]]||S
|-
|-
| ||[[Metronidazole]]||0
| ||[[Metronidazole]]||R
|-
|-
| ||Quinupristin dalfoppristin||+
| ||Quinupristin dalfoppristin||S
|-
|-
| ||Linezolid||+
| ||[[Linezolid]]||S
|-
|-
| ||[[Daptomycin]]||+
| ||Colistimethate||R
|-
| ||Colistimethate||0
|}
|}


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==See Also==
==See Also==
*[[Microbiology (Main)]]
*[[Microbiology (Main)]]
*[[Staphylococcus]]


==References==
==References==

Latest revision as of 06:43, 3 June 2014

Background

Antibiotic Sensitivities[1]

Category Antibiotic Staph. Epidermidis
Penicillins Penicillin G R
Penicillin V R
Methicillin S
Nafcillin/Oxacillin S
Cloxacillin/Diclox. S
Amino-Penicillins AMP/Amox R
Amox-Clav R
AMP-Sulb R
Anti-Pseudomonal Penicillins Ticarcillin I
Ticar-Clav I
Pip-Tazo S
Piperacillin R
Carbapenems Doripenem S
Ertapenem S
Imipenem S
Meropenem S
Aztreonam R
Fluroquinolones Ciprofloxacin S
Ofloxacin S
Pefloxacin S
Levofloxacin S
Moxifloxacin S
Gemifloxacin S
Gatifloxacin S
1st G Cephalo Cefazolin I
2nd G. Cephalo Cefotetan I
Cefoxitin I
Cefuroxime I
3rd/4th G. Cephalo Cefotaxime I
Cefizoxime I
CefTRIAXone I
Ceftaroline S
CefTAZidime I
Cefepime I
Oral 1st G. Cephalo Cefadroxil I
Cephalexin I
Oral 2nd G. Cephalo Cefaclor/Loracarbef I
Cefproxil I
Cefuroxime axetil I
Oral 3rd G. Cephalo Cefixime R
Ceftibuten R
Cefpodox/Cefdinir/Cefditoren I
Aminoglycosides Gentamicin I
Tobramycin I
Amikacin I
Chloramphenicol R
Clindamycin R
Macrolides Erythromycin I
Azithromycin R
Clarithromycin R
Ketolide Telithromycin R
Tetracyclines Doxycycline R
Minocycline R
Glycylcycline Tigecycline S
Daptomycin S
Glyco/Lipoclycopeptides Vancomycin S
Teicoplanin I
Telavancin S
Fusidic Acid S
Trimethoprim S
TMP-SMX I
Urinary Agents Nitrofurantoin X1
Fosfomycin X1
Other Rifampin S
Metronidazole R
Quinupristin dalfoppristin S
Linezolid S
Colistimethate R

Key

  • S susceptible/sensitive (usually)
  • I intermediate (variably susceptible/resistant)
  • R resistant (or not effective clinically)
  • S+ synergistic with cell wall antibiotics
  • U sensitive for UTI only (non systemic infection)
  • X1 no data
  • X2 active in vitro, but not used clinically
  • X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
  • X4 active in vitro, but not clinically effective for strep pneumonia

Table Overview

Gram Positives
Cocci
Clusters
Pairs/Chains
Other
Rods
Gram Negatives
Cocci
Rods
Lactose Fermenters
Lactose Non-Fermenters
Other
Rods/Cocci
Anaerobes

See Also

References

  1. ↑ Sanford Guide to Antimicrobial Therapy 2014
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