Staphylococcus epidermidis

Background

Organisms	'	Staph. epidermidis
Penicillins	Penicillin G	0
	Penicillin V	0
Anti-Staphylocccal Penicillins	Methicillin	+
	Nafcillin/Oxacillin	+
	Cloxacillin/Diclox.	+
Amino-Penicillins	AMP/Amox	0
	Amox/Clav	0
	AMP-Sulb	0
Anti-Pseudomonal Penicillins	Ticarcillin	+/-
	Ticar-Clav	+/-
	Pip-Taxo	+
Carbapenems	Piperacillin	0
	Doripenem	+
	Ertapenem	+
	Imipenem	+
	Meropenem	+
	Aztreonam	0
Fluroquinolones	Ciprofloxacin	+
	Ofloxacin	+
	Pefloxacin	+
	Levofloxacin	+
	Moxifloxacin	+
	Gemifloxacin	+
	Gatifloxacin	+
1st G Cephalosporin	Cefazolin	+/-
2nd G. Cephalosporin	Cefotetan	+/-
	Cefoxitin	+/-
	Cefuroxime	+/-
3rd/4th G. Cephalosporin	CefoTAXime	+/-
	Cefizoxime	+/-
	CefTRIAXone	+/-
	Ceftobiprole	+
	Ceftaroline	+
	CefTAZidime	+/-
	Cefepime	+/-
Oral 1st G. Cephalosporin	Cefadroxil	+/-
	Cephalexin	+/-
Oral 2nd G. Cephalosporin	Cefaclor/Loracarbef	+/-
	Cefproxil	+/-
	Cefuroxime axetil	+/-
Oral 3rd G. Cephalosporin	Cefixime	0
	Ceftibuten	0
	Cefpodox/Cefdinir/Cefditoren	+/-
Aminoglycosides	Gentamicin	+/-
	Tobramycin	+/-
	Amikacin	+/-
	Chloramphenicol	0
	Clindamycin	0
Macrolides	Erythromycin	+/-
	Azithromycin	0
	Clarithromycin	0
Ketolide	Telithromycin	0
Tetracyclines	Doxycycline	0
	Minocycline	0
Glycylcycline	Tigecycline	+
Glyco/Lipoclycopeptides	Vancomycin	+
	Teicoplanin	+/-
	Telavancin	+
	Fusidic Acid	+
	Trimethoprim	+
	TMP-SMX	+/-
Urinary Agents	Nitrofurantoin
	Fosfomycin
Other	Rifampin	+
	Metronidazole	0
	Quinupristin dalfoppristin	+
	Linezolid	+
	Daptomycin	+
	Colistimethate	0

S susceptible/sensitive (usually)
I intermediate (variably susceptible/resistant)
R resistant (or not effective clinically)
S+ synergistic with cell wall antibiotics
U sensitive for UTI only (non systemic infection)
X1 no data
X2 active in vitro, but not used clinically
X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
X4 active in vitro, but not clinically effective for strep pneumonia

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