Sympathomimetic toxicity: Difference between revisions

(Text replacement - "==Treatment==" to "==Management==")
No edit summary
Line 12: Line 12:
==Complications==
==Complications==
*[[Rhabdomyolysis]] is common complication <ref name="tox">O'Connor AD, Padilla-Jones A, Gerkin AD, et al.  Prevalence of Rhabdomyolysis in Sympathomimetic Toxicity: a Comparison of Stimulants. J Med Toxicol 2015;11(2)195-200</ref>
*[[Rhabdomyolysis]] is common complication <ref name="tox">O'Connor AD, Padilla-Jones A, Gerkin AD, et al.  Prevalence of Rhabdomyolysis in Sympathomimetic Toxicity: a Comparison of Stimulants. J Med Toxicol 2015;11(2)195-200</ref>
 
**[[Bath Salts]] -  63% <ref name="tox"></ref>
*[[Bath Salts]] -  63% <ref name="tox"></ref>
**[[Amphetamines]] - 40%
*[[Amphetamines]] - 40%
**[[Cocaine]] - 33%
*[[Cocaine]] - 33%


==See Also==
==See Also==

Revision as of 12:23, 14 October 2016

Types

Sympathomimetics

Differential Diagnosis

Altered mental status and fever

Toxidrome Chart

Finding Cholinergic Anticholinergic Sympathomimetic Sympatholytic^ Sedative/Hypnotic
Example Organophosphates TCAs Cocaine Clonidine ETOH
Temp Nl Nl / ↑ Nl / ↑ Nl / ↓ Nl / ↓
RR Variable Nl / ↓ Variable Nl / ↓ Nl / ↓
HR Variable ↑ (sig) Nl / ↓ Nl / ↓
BP Nl / ↓ Nl / ↓
LOC Nl / Lethargic Nl, agitated, psychotic, comatose Nl, agitated, psychotic Nl, Lethargic, or Comatose Nl, Lethargic, or Comatose
Pupils Variable Mydriatic Mydriatic Nl / Miotic
Motor Fasciculations, Flacid Paralysis  Nl Nl / Agitated Nl
Skin Sweating (sig) Hot, dry Sweating Dry
Lungs Bronchospasm / rhinorrhea Nl Nl Nl
Bowel Sounds Hyperactive (SLUDGE) ↓ / Absent Nl / ↓ Nl / ↓
^Consider Sympatholytic when looking at Sedative OD or someone who doesn't respond to Narcan
Withdrawal from substances have the opposite effect

Management

Complications

See Also

References

  1. 1.0 1.1 O'Connor AD, Padilla-Jones A, Gerkin AD, et al. Prevalence of Rhabdomyolysis in Sympathomimetic Toxicity: a Comparison of Stimulants. J Med Toxicol 2015;11(2)195-200