Difference between revisions of "Systemic lupus erythematosus"

(See Also)
Line 36: Line 36:
 
***Infectious and Libman-Sachs
 
***Infectious and Libman-Sachs
  
*Neuropsychartic/Altered mental status
+
*Neuropsychiatric/Altered mental status
 
**Non-convulsive status epilepticus
 
**Non-convulsive status epilepticus
 
**CNS vasculitis
 
**CNS vasculitis
 
**[[Stroke]]
 
**[[Stroke]]
 
**[[Encephalitis]]
 
**[[Encephalitis]]
 
  
 
*Musculoskeletal
 
*Musculoskeletal
 
+
**Arthritis
 +
***Usually symmetric
 +
***Consider septic arthritis if there is a single inflamed joint
 +
****Cover for [[''Salmonella'']] in addition to standard coverage
  
 
==Differential Diagnosis==
 
==Differential Diagnosis==

Revision as of 22:25, 25 March 2014

Background

  • Autoimmune disorder affecting all sysems

Epidemiology

  • Femaile:Male 10:1
  • More common in African Americans


Clinical Features

Diagnostic Criteria: 4 out of 11 of the following:

  1. Malar rash
  2. Discoid rash
  3. Photosensitivity
  4. Oral ulcers
  5. Arthritis (polyarticular)
  6. Serositis (Pericarditis or pleuritis)
  7. Renal disorder (renal failure, protenuria, casts)
  8. Neurologic or psychotic symptoms
  9. Hematologic (anemia, thrombocytopenia, or leukopenia)
  10. Immunologic (+antibofy testing)
  11. ANA (positive ANA)

New Presentations


Flairs

  • Neuropsychiatric/Altered mental status
  • Musculoskeletal
    • Arthritis
      • Usually symmetric
      • Consider septic arthritis if there is a single inflamed joint

Differential Diagnosis

Workup

Undiagnosed

  • CBC
  • Chem 10
  • ANA
  • ESR
  • UA
  • Bedside echo if ill or hypotensive

Flair

  • Bedside echo if ill or hypotensive
  • CBC



Management

  • Steroids


Disposition

See Also

Sources

  • Rosen's
  • Up to date