Systemic lupus erythematosus
Revision as of 20:49, 25 March 2014 by Rossdonaldson1 (talk | contribs) (Rossdonaldson1 moved page Systemic lupus erythematosus to Systemic Lupus Erythematosus)
Background
- Autoimmune disorder
Epidemiology
- Femaile:Male 10:1
- More common in African Americans
Clinical Features
Diagnostic Criteria: 4 out of 11 of the following:
- Malar rash
- Discoid rash
- Photosensitivity
- Oral ulcers
- Arthritis (polyarticular)
- Serositis (Pericarditis or pleuritis)
- Renal disorder (renal failure, protenuria, casts)
- Neurologic or psychotic symptoms
- Hematologic (anemia, thrombocytopenia, or leukopenia)
- Immunologic (+antibofy testing)
- ANA (positive ANA)
New Presentations
Flairs
Differential Diagnosis
- Rheumatoid arthritis
- Sjogren's syndrome
- Dermatomyositis
- Polymyositis
- Stevens-Johnson syndrome
- Toxic Epidermal Necrolysis
- Septic arthritis
- Lyme disease
- Vasculitis
- Acute Rheumatic Fever
- Toxic Shock Syndrome
- TTP
- ITP
- DIC
Workup
Undiagnosed
- CBC
- Chem 10
- ANA
- ESR
- UA
- Bedside echo if ill or hypotensive
Flair
- Bedside echo if ill or hypotensive
- CBC
Management
- Steroids
Disposition
See Also
Arthritis Fever and Rash Lupus Anticoagulant Pericarditis Pericardial Effusion and Tamponade Acute Renal Failure Adrenal Crisis
Sources
- Rosen's
- Up to date