Systemic lupus erythematosus

Background

• Autoimmune disorder

Epidemiology

• Femaile:Male 10:1
• More common in African Americans

Clinical Features

Diagnostic Criteria:

New Presentations

Flairs

Differential Diagnosis

• Rheumatoid arthritis
• Sjogren's syndrome
• Dermatomyositis
• Polymyositis
• Stevens-Johnson syndrome
• Toxic Epidermal Necrolysis
• Septic arthritis
• Lyme disease
• Vasculitis
• Acute Rheumatic Fever
• Toxic Shock Syndrome
• TTP
• ITP
• DIC

Undiagnosed

• CBC
• Chem 10
• ANA
• ESR
• UA
• Bedside echo if ill appearing

Flair

• Bedside echo if ill or hypotensive
• CBC

See Also

Arthritis Fever and Rash Lupus Anticoagulant Pericarditis Acute Renal Failure Adrenal Crisis

Sources

• Rosen's
• Up to date