Template:ACLS Wide Regular Tachycardia: Difference between revisions

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*'''Stable''':
*'''Stable''':
*#Medications
*#Medications
*#*[[Procainamide]] (first line drug of choice)
*#*[[Procainamide]] (first-line drug of choice)
*#**20-50mg/min until arrhythmia suppressed (max 17mg/kg or 1 gram); then, maintenance infusion of 1-4mg/min x 6hr
*#**20-50mg/min until arrhythmia suppressed (max 17mg/kg or 1 gram); then, maintenance infusion of 1-4mg/min x 6hr
*#***Alternative administration: 100 mg q5min at max rate of 25-50 mg/min<ref>Procainamide. GlobalRPH. http://www.globalrph.com/procainamide_dilution.htm.</ref>
*#***Alternative administration: 100 mg q5min at max rate of 25-50 mg/min<ref>Procainamide. GlobalRPH. http://www.globalrph.com/procainamide_dilution.htm.</ref>
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*#**Avoid if [[prolonged QT]] or [[CHF]]
*#**Avoid if [[prolonged QT]] or [[CHF]]
*#**Favored over Amiodarone in PROCAMIO trial; termination of tachycardia in 67% of procainamide group vs 38% of amiodarone group, adverse cardiac events 9% vs 41%, respectively <ref>Ortiz M, Martín A, Arribas F, et al. Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study. Eur Heart J. 2017 May 1;38(17):1329-1335</ref>
*#**Favored over Amiodarone in PROCAMIO trial; termination of tachycardia in 67% of procainamide group vs 38% of amiodarone group, adverse cardiac events 9% vs 41%, respectively <ref>Ortiz M, Martín A, Arribas F, et al. Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study. Eur Heart J. 2017 May 1;38(17):1329-1335</ref>
*#*[[Amiodarone]], agent of choice in setting of AMI or LV dysfunction
*#*[[Amiodarone]] (agent of choice in setting of [[AMI]] or LV dysfunction)
*#**150 mg over 10min (15 mg/min), followed by 1 mg/min drip over 6hrs (360 mg total)<ref>Amiodarone. GlobalRPH. http://www.globalrph.com/amiodarone_dilution.htm.</ref>
*#**150 mg over 10min (15 mg/min), followed by 1 mg/min drip over 6hrs (360 mg total)<ref>Amiodarone. GlobalRPH. http://www.globalrph.com/amiodarone_dilution.htm.</ref>
*#**Then 0.5 mg/min drip over next 18 hrs (540 mg total)
*#**Then 0.5 mg/min drip over next 18 hrs (540 mg total)
*#**Oral dosage after IV infusion is 400 -800 mg PO daily  
*#**Oral dosage after IV infusion is 400 -800 mg PO daily  
*#*[[Adenosine]]
*#*Consider [[adenosine]]
*#**May be considered for diagnosis and treatment only if rhythm is regular and monomorphic
*#**Consider for diagnosis and treatment, if rhythm is regular and monomorphic (see [[rhythm diagnosis in regular wide complex tachycardia]])
*#**6 mg IV as a rapid IV push followed by a 20 mL saline flush; repeat if required as 12 mg IV push
*#**6 mg IV as a rapid IV push followed by a 20 mL saline flush; repeat if required as 12 mg IV push
*#Synchronized [[Cardioversion]] (100J)
*#Synchronized [[Cardioversion]] (100J)

Revision as of 12:10, 14 March 2018

Wide Regular Tachycardia[1]

Pulseless: see Adult pulseless arrest

  • Unstable: Hypotension, altered mental status, shock, ischemic chest discomfort, acute heart failure
  • Stable:
    1. Medications
      • Procainamide (first-line drug of choice)
        • 20-50mg/min until arrhythmia suppressed (max 17mg/kg or 1 gram); then, maintenance infusion of 1-4mg/min x 6hr
          • Alternative administration: 100 mg q5min at max rate of 25-50 mg/min[2]
        • Stop if QRS duration increases >50% or hypotension
        • Avoid if prolonged QT or CHF
        • Favored over Amiodarone in PROCAMIO trial; termination of tachycardia in 67% of procainamide group vs 38% of amiodarone group, adverse cardiac events 9% vs 41%, respectively [3]
      • Amiodarone (agent of choice in setting of AMI or LV dysfunction)
        • 150 mg over 10min (15 mg/min), followed by 1 mg/min drip over 6hrs (360 mg total)[4]
        • Then 0.5 mg/min drip over next 18 hrs (540 mg total)
        • Oral dosage after IV infusion is 400 -800 mg PO daily
      • Consider adenosine
    2. Synchronized Cardioversion (100J)
  1. American Heart Association. Web-based Integrated Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care – Part 7: Adult Advanced Cardiovascular Life Support. ECCguidelines.heart.org
  2. Procainamide. GlobalRPH. http://www.globalrph.com/procainamide_dilution.htm.
  3. Ortiz M, Martín A, Arribas F, et al. Randomized comparison of intravenous procainamide vs. intravenous amiodarone for the acute treatment of tolerated wide QRS tachycardia: the PROCAMIO study. Eur Heart J. 2017 May 1;38(17):1329-1335
  4. Amiodarone. GlobalRPH. http://www.globalrph.com/amiodarone_dilution.htm.