Template:BV Antibiotics: Difference between revisions

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(updated treatment per CDC)
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*[[Metronidazole]] 2g PO once
====First Line Therapy<ref>Workoski KA and Bolan GA. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recommen and Reports. 2015; 64(3):1-140.</ref>====
**Adolescent '''<45kg:''' 15 mg/kg/day PO divided q8h x 7 days OR 7mg/kg PO x 1
*[[Metronidazole]] 500 mg PO BID for 7 days OR
**Adolescent '''>45kg:'''2g PO x 1
*[[Metronidazole]] gel 0.75%, one full applicator (5 g) intravaginally, qd for 5 days OR
*[[Clindamycin]] 300mg PO BID x 7 days
*[[Clindamycin]] cream 2%, one full applicator (5 g) intravaginally qHS for 7 days
 
====Alternative Regimine====
*[[Tinidazole]] 2 g PO qd for 2 days OR
*[[Tinidazole]] 1 g PO qd for 5 days OR
*[[Clindamycin]] 300 mg PO BID for 7 days OR
*[[Clindamycin]] ovules 100 mg intravaginally qHS for 3 days (do not use if patient has used latex condom in last 72 hrs)


====Pregnancy====
====Pregnancy====
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====Prophylaxis ([[Sexual Assault]])====
====Prophylaxis ([[Sexual Assault]])====
*[[Metronidazole]] 2 g PO x 1 OR
*[[Metronidazole]] 2 g PO x 1 OR
*[[Clindamycin]] 300mg PO BID x 7 days
*[[Tinidazole]] 2 g PO x 1

Revision as of 14:47, 5 June 2015

First Line Therapy[1]

  • Metronidazole 500 mg PO BID for 7 days OR
  • Metronidazole gel 0.75%, one full applicator (5 g) intravaginally, qd for 5 days OR
  • Clindamycin cream 2%, one full applicator (5 g) intravaginally qHS for 7 days

Alternative Regimine

  • Tinidazole 2 g PO qd for 2 days OR
  • Tinidazole 1 g PO qd for 5 days OR
  • Clindamycin 300 mg PO BID for 7 days OR
  • Clindamycin ovules 100 mg intravaginally qHS for 3 days (do not use if patient has used latex condom in last 72 hrs)

Pregnancy

  • Alternative: 250mg PO q8h x 7 days in pregnant patients[2]
  • 2g PO x 1 is also acceptable in pregnancy[2]
  • Multiple studies have not demonstrated teratogenicity from metronidazole use[2]

Prophylaxis (Sexual Assault)

  1. Workoski KA and Bolan GA. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recommen and Reports. 2015; 64(3):1-140.
  2. 2.0 2.1 2.2 CDC Pregnancy BV Treatment Guidelines.cdc.gov