Template:BV Antibiotics: Difference between revisions

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*[[Metronidazole]] 2g PO once
====First Line Therapy<ref>Workoski KA and Bolan GA. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recommen and Reports. 2015; 64(3):1-140.</ref>====
**Adolescent '''<45kg:''' 15 mg/kg/day PO divided q8h x 7 days OR 7mg/kg PO x 1
*[[Metronidazole]] 500 mg PO BID for 7 days OR
**Adolescent '''>45kg:'''2g PO x 1
*[[Metronidazole]] gel 0.75%, one full applicator (5 g) intravaginally, qd for 5 days OR
*[[Clindamycin]] 300mg PO BID x 7 days
*[[Clindamycin]] cream 2%, one full applicator (5 g) intravaginally qHS for 7 days


====Pregnancy====
====Alternative Regimin====
*Alternative: 250mg PO q8h x 7 days in pregnant patients<ref name="cdc">CDC Pregnancy BV Treatment Guidelines.[http://www.cdc.gov/std/treatment/2010/vaginal-discharge.htm#a1 cdc.gov]</ref>
*[[Tinidazole]] 2 g PO qd for 2 days OR
*2g PO x 1 is also acceptable in pregnancy<ref name="cdc"></ref>
*[[Tinidazole]] 1 g PO qd for 5 days OR
* Multiple studies have not demonstrated teratogenicity from metronidazole use<ref name="cdc"></ref>
*[[Clindamycin]] 300 mg PO BID for 7 days OR
*[[Clindamycin]] ovules 100 mg intravaginally qHS for 3 days (do not use if patient has used latex condom in last 72 hrs)
 
====Pregnant====
*[[Metronidazole]] 250mg PO q8h x 7 days<ref name="cdc">CDC Pregnancy BV Treatment Guidelines.[http://www.cdc.gov/std/treatment/2010/vaginal-discharge.htm#a1 cdc.gov]</ref>
*[[Metronidazole]] 2g PO x 1 dose is also acceptable<ref name="cdc" />
* Multiple studies have not demonstrated teratogenicity from metronidazole use<ref name="cdc" />


====Prophylaxis ([[Sexual Assault]])====
====Prophylaxis ([[Sexual Assault]])====
*[[Metronidazole]] 2 g PO x 1 OR
*[[Metronidazole]] 2 g PO x 1 OR
*[[Clindamycin]] 300mg PO BID x 7 days
*[[Tinidazole]] 2 g PO x 1

Latest revision as of 04:27, 18 August 2015

First Line Therapy[1]

  • Metronidazole 500 mg PO BID for 7 days OR
  • Metronidazole gel 0.75%, one full applicator (5 g) intravaginally, qd for 5 days OR
  • Clindamycin cream 2%, one full applicator (5 g) intravaginally qHS for 7 days

Alternative Regimin

  • Tinidazole 2 g PO qd for 2 days OR
  • Tinidazole 1 g PO qd for 5 days OR
  • Clindamycin 300 mg PO BID for 7 days OR
  • Clindamycin ovules 100 mg intravaginally qHS for 3 days (do not use if patient has used latex condom in last 72 hrs)

Pregnant

Prophylaxis (Sexual Assault)

  1. Workoski KA and Bolan GA. Sexually transmitted diseases treatment guidelines, 2015. MMWR Recommen and Reports. 2015; 64(3):1-140.
  2. 2.0 2.1 2.2 CDC Pregnancy BV Treatment Guidelines.cdc.gov