Thyroid disease (main)

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  1. Cretinism - no congenital T3 or T4
  2. Parafollicular C cells make calcitonin to keep the bone in
  3. Endemic goiter- if patient from area of low iodine intake
  4. Free t3 & t4 determines thyroid state - not total plasma conc
  5. T4-> T3 active & rt3 inactive
  6. TRH -> TSH -> T4 -> T3

Thyroid Studies and Etiologies

Thyroid studies.JPG
  • Hyperthyroidism
  • Subclinical hyperthyroidism
  • T3 toxicosis
  • Thyroiditis, T4 ingestion, hyperthyroidism of elderly or cormorbid illness
  • Euthyroid sick syndrome, central hypothyroidism
  • Subclinical hypothyroidism, recovery from euthyroid sick syndrome
  • Primary hypothyroidism
  • TSH producing pituitary adenoma

See Also


  • Sharma AN, Levy DL; Thyroid and Adrenal Disorders; in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2014, (Ch) 128: p 1676-1693.
  • Agus, MSD: Chapter 86 – Endocrine Emergencies, in Fleisher & Ludwig’s Textbook of Pediatric EM, 6th Ed., Lippincott Williams & Williams, 2010, p. 779-780