Tianeptine: Difference between revisions
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===Serious=== | ===Serious=== | ||
*[[Hepatotoxicity]] | *[[Hepatotoxicity]] | ||
*Respiratory depression | |||
*[[Altered mental status]] | |||
*[[Coma]] | |||
===Common=== | ===Common=== |
Revision as of 19:41, 4 August 2020
Administration
- Type: Antidepressant
- Dosage Forms: 12.5mg tablet
- Routes of Administration: Oral
- Common Trade Names: Coaxil, Stablon
Adult Dosing
- 12.5mg PO three times daily before meals
- >70 years old - 12.5mg PO two times daily before meals
Pediatric Dosing
N/A
Special Populations
Pregnancy Rating
- N/A
Lactation risk
- N/A
Renal Dosing
- Adult:N/A
- Pediatric:N/A
Hepatic Dosing
- Adult:N/A
- Pediatric:N/A
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- Hepatotoxicity
- Respiratory depression
- Altered mental status
- Coma
Common
- Nausea
- Constipation
- Abdominal pain
- Headache
- Dizziness
- Changes in dreaming
- Anticholinergic effects
Pharmacology
- Half-life: 1.5 hours
- Metabolism: Hepatic
- Excretion: Renal
Mechanism of Action
- Serotonin reuptake enhancement, glutamate receptor inhibitor, μ-opiod receptor agonist
Comments
- Not FDA approved