Difference between revisions of "Transfusion-related acute lung injury"

(Differential Diagnosis)
(Management)
Line 16: Line 16:
  
 
==Management==
 
==Management==
**Strop transfusion
+
*Strop transfusion
**Treat like [[ARDS]]
+
*Treat like [[ARDS]]
**Avoid diuresis
+
*Avoid diuresis
  
 
==Disposition==
 
==Disposition==

Revision as of 20:59, 4 February 2016

Background

  • Due to granulocyte recruitment and degranulation within the lung
  • More common with FFP and platelet transfusions (extremely rare with pRBC transfusion alone)
    • pRBCs do contain residual plasma and can have TRALI

Clinical Features

Differential Diagnosis

Transfusion Reaction Types

Acute allergic reaction

Diagnosis

  • Time Frame: abrupt to within 6 hours of transfusion initiation

Management

  • Strop transfusion
  • Treat like ARDS
  • Avoid diuresis

Disposition

  • Bilateral pulmonary infiltrates due to noncardiogenic pulmonary edema within 6h of transfusion

See Also

External Links

References