Difference between revisions of "United States Antibiogram"

(Gram Positives)
(Gram Positives)
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==[[Gram Positives]]==
 
==[[Gram Positives]]==
 
{| class="wikitable"
 
{| class="wikitable"
| align="center" style="background:#f0f0f0;"|'''Category'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''Antibiotic'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[Strep. Group A, B, C, G]]'''
+
| align="center" style="background:#f0f0f0;"|'''Gram Positive'''
| align="center" style="background:#f0f0f0;"|'''[[Strep. Pneumoniae]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[Viridans strep]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[Strep. milleri]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[Enterococcus faecalis]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[Enterococcus faecium]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''Staph. aureus ([[MSSA]])'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''Staph. aureus ([[MRSA]])'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''Staph. aureus ([[CA-MRSA]])'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[Staph. Epidermidis]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[C. jeikeium]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
| align="center" style="background:#f0f0f0;"|'''[[L. monocytogenes]]'''
+
| align="center" style="background:#f0f0f0;"|''''''
 
|-
 
|-
| Penicillins||[[Penicillin G]]||+||+||+/-||+||+||+/-||0||0||0||0||0||+
+
| Category||Antibiotic||[[Strep. Group A, B, C, G]]||[[Strep. Pneumoniae]]||[[Viridans strep]]||[[Strep. milleri]]||[[Enterococcus faecalis]]||[[Enterococcus faecium]]||Staph. aureus ([[MSSA]])||Staph. aureus ([[MRSA]])||Staph. aureus ([[CA-MRSA]])||[[Staph. Epidermidis]]||[[C. jeikeium]]||[[L. monocytogenes]]
 +
|-
 +
| [[Penicillins]]||[[Penicillin G]]||+||+||+/-||+||+||+/-||0||0||0||0||0||+
 
|-
 
|-
 
| ||[[Penicillin V]]||+||+||+/-||+||+||+/-||0||0||0||0||0||0
 
| ||[[Penicillin V]]||+||+||+/-||+||+||+/-||0||0||0||0||0||0
 
|-
 
|-
| Anti-Staphylocccal Penicillins||Methicillin||+||+||+/-||+||0||0||+||0||0||+||0||0
+
| Anti-Staphylocccal [[Penicillins]]||Methicillin||+||+||+/-||+||0||0||+||0||0||+||0||0
 
|-
 
|-
 
| ||Nafcillin/Oxacillin||+||+||+/-||+||0||0||+||0||0||+||0||0
 
| ||Nafcillin/Oxacillin||+||+||+/-||+||0||0||+||0||0||+||0||0
 
|-
 
|-
| ||Cloxacillin/Diclox.||+||+||+/-||+||0||0||+||0||0||+||0||0
+
| ||Dicloxacillin||+||+||+/-||+||0||0||+||0||0||+||0||0
 
|-
 
|-
| Amino-Penicillins||[[AMP]]/[[Amox]]||+||+||+/-||+||+||+||0||0||0||0||0||+
+
| Amino-[[Penicillins]]||[[AMP]]/[[Amox]]||+||+||+/-||+||+||+||0||0||0||0||0||+
 
|-
 
|-
 
| ||[[Amox-Clav]]||+||+||+/-||+||+||+||+||0||0||0||0||
 
| ||[[Amox-Clav]]||+||+||+/-||+||+||+||+||0||0||0||0||
Line 32: Line 34:
 
| ||[[AMP-Sulb]]||+||+||+/-||+||+||+||+||0||0||0||0||+
 
| ||[[AMP-Sulb]]||+||+||+/-||+||+||+||+||0||0||0||0||+
 
|-
 
|-
| Anti-Pseudomonal Penicillins||Ticarcillin||+||+||+/-||+||+/-||+/-||0||0||0||+/-||0||+
+
| Anti-Pseudomonal [[Penicillins]]||[[Ticarcillin]]||+||+||+/-||+||+/-||+/-||0||0||0||+/-||0||+
 
|-
 
|-
 
| ||[[Ticar-Clav]]||+||+||+/-||+||+/-||+/-||+||0||0||+/-||0||
 
| ||[[Ticar-Clav]]||+||+||+/-||+||+/-||+/-||+||0||0||+/-||0||
Line 38: Line 40:
 
| ||[[Pip-Tazo]]||+||+||+/-||+||+||+/-||+||0||0||+||||
 
| ||[[Pip-Tazo]]||+||+||+/-||+||+||+/-||+||0||0||+||||
 
|-
 
|-
| [[Carbapenems]]||Piperacillin||+||+||+/-||+||+||+/-||0||0||0||0||0||+
+
| [[Carbapenems]]||Doripenem||+||+||+||+||+/-||0||+||0||0||+||||+
|-
 
| ||Doripenem||+||+||+||+||+/-||0||+||0||0||+||||+
 
 
|-
 
|-
 
| ||[[Ertapenem]]||+||+||+||+||0||0||+||0||0||+||0||+/-
 
| ||[[Ertapenem]]||+||+||+||+||0||0||+||0||0||+||0||+/-
Line 53: Line 53:
 
|-
 
|-
 
| ||[[Ofloxacin]]||+/-||+/-||0||0||^^||0||+||0||||+||0||0
 
| ||[[Ofloxacin]]||+/-||+/-||0||0||^^||0||+||0||||+||0||0
|-
 
| ||Pefloxacin||0||0||||||0||0||+||0||||+||||0
 
 
|-
 
|-
 
| ||[[Levofloxacin]]||+||+||+||+||+||0||+||0||+/-||+||||+
 
| ||[[Levofloxacin]]||+||+||+||+||+||0||+||0||+/-||+||||+
Line 64: Line 62:
 
| ||Gatifloxacin||+||+||+||+||+||+/-||+||+/-||+/-||+||||+
 
| ||Gatifloxacin||+||+||+||+||+||+/-||+||+/-||+/-||+||||+
 
|-
 
|-
| 1st G [[Cephalosporins]]||Cefazolin||+||+||+||||0||||+||0||0||+/-||0||0
+
| 1st G [[Cephalo]]||Cefazolin||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
| 2nd G. [[Cephalosporins]]||[[Cefotetan]]||+||+||+||||0||||+||0||0||+/-||0||0
+
| 2nd G [[Cephalo]]||[[Cefotetan]]||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
 
| ||[[Cefoxitin]]||+||+||+||||0||||+||0||0||+/-||0||0
 
| ||[[Cefoxitin]]||+||+||+||||0||||+||0||0||+/-||0||0
Line 72: Line 70:
 
| ||[[Cefuroxime]]||+||+||+||||0||||+||0||0||+/-||0||0
 
| ||[[Cefuroxime]]||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
| 3rd/4th G. [[Cephalosporins]]||[[Cefotaxime]]||+||+||+||||0||||+||0||0||+/-||0||0
+
| 3rd/4th G [[Cephalo]]||[[Cefotaxime]]||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
 
| ||Cefizoxime||+||+||+||||0||||+||0||0||+/-||0||0
 
| ||Cefizoxime||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
 
| ||[[CefTRIAXone]]||+||+||+||||0||||+||0||0||+/-||0||0
 
| ||[[CefTRIAXone]]||+||+||+||||0||||+||0||0||+/-||0||0
|-
 
| ||Ceftobiprole||+||+||+||||+||||+||+||+||+||||
 
 
|-
 
|-
 
| ||Ceftaroline||+||+||+||||+||||+||+||+||+||||
 
| ||Ceftaroline||+||+||+||||+||||+||+||+||+||||
Line 86: Line 82:
 
| ||[[Cefepime]]||+||+||+||||0||||+||0||0||+/-||||0
 
| ||[[Cefepime]]||+||+||+||||0||||+||0||0||+/-||||0
 
|-
 
|-
| Oral 1st G. [[Cephalosporins]]||Cefadroxil||+||+||+||||0||||+||0||0||+/-||0||0
+
| Oral 1st G [[Cephalo]]||Cefadroxil||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
 
| ||[[Cephalexin]]||+||+||+||||0||||+||0||0||+/-||0||0
 
| ||[[Cephalexin]]||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
| Oral 2nd G. [[Cephalosporins]]||Cefaclor/Loracarbef||+||+||+||||0||||+||0||0||+/-||0||0
+
| Oral 2nd G [[Cephalo]]||Cefaclor||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
 
| ||Cefproxil||+||+||0||||0||||+||0||0||+/-||0||0
 
| ||Cefproxil||+||+||0||||0||||+||0||0||+/-||0||0
 
|-
 
|-
| ||Cefuroxime axetil||+||+||+||||0||||+||0||0||+/-||0||0
+
| ||Cefuroxime||+||+||+||||0||||+||0||0||+/-||0||0
 
|-
 
|-
| Oral 3rd G. [[Cephalosporins]]||Cefixime||+||+||+||||0||||0||0||0||0||0||0
+
| Oral 3rd G [[Cephalo]]||Cefixime||+||+||+||||0||||0||0||0||0||0||0
 
|-
 
|-
 
| ||Ceftibuten||+||+/-||0||||0||||0||0||0||0||0||0
 
| ||Ceftibuten||+||+/-||0||||0||||0||0||0||0||0||0
 
|-
 
|-
| ||Cefpodox/Cefdinir/Cefditoren||+||+||+||||0||||+||0||0||+/-||||0
+
| ||Cefpodox/ Cefdinir/ Cefditoren||+||+||+||||0||||+||0||0||+/-||||0
 
|-
 
|-
 
| [[Aminoglycosides]]||[[Gentamicin]]||0||0||||||S||S||+||0||||+/-||0||S
 
| [[Aminoglycosides]]||[[Gentamicin]]||0||0||||||S||S||+||0||||+/-||0||S
Line 126: Line 122:
 
| Glycylcycline||Tigecycline||+||+||||||+||+||+||+||+||+||+||+
 
| Glycylcycline||Tigecycline||+||+||||||+||+||+||+||+||+||+||+
 
|-
 
|-
| Glycopeptides||[[Vancomycin]]||+||+||||||+||+/-||+||+||+||+||+||+
+
| Sulfonamides||[[TMP-SMX]]||+||+||||||+||0||+||+||+||+/-||0||+
|-
 
| ||Teicoplanin||+||+||||||+||+/-||+||+||+||+/-||+||+
 
|-
 
| ||Telavancin||+||+||||||+||+||+||+||+||+||+||+
 
|-
 
| ||Fusidic Acid||+/-||+/-||||||+||||+||+||+||+||+||
 
|-
 
| ||Trimethoprim||+||+/-||||||+||0||+/-||+/-||+||+||0||+
 
|-
 
| ||[[TMP-SMX]]||+||+||||||+||0||+||+||+||+/-||0||+
 
 
|-
 
|-
 
| Urinary Agents||[[Nitrofurantoin]]||+||+||||||+||+||+||+||+||||0||
 
| Urinary Agents||[[Nitrofurantoin]]||+||+||||||+||+||+||+||+||||0||
Line 146: Line 132:
 
| ||[[Metronidazole]]||0||0||||||0||0||0||0||0||0||+||0
 
| ||[[Metronidazole]]||0||0||||||0||0||0||0||0||0||+||0
 
|-
 
|-
| ||Quinupristin dalfoppristin||+||+||||||0||+||+||+||+||+||+||+
+
| ||Quinupristin-dalfoppristin||+||+||||||0||+||+||+||+||+||+||+
 
|-
 
|-
 
| ||[[Linezolid]]||+||+||||||+||+||+||+||+||+||+||+
 
| ||[[Linezolid]]||+||+||||||+||+||+||+||+||+||+||+
Line 153: Line 139:
 
|-
 
|-
 
| ||Colistimethate||0||0||||||0||0||0||0||0||0||||0
 
| ||Colistimethate||0||0||||||0||0||0||0||0||0||||0
 +
|-
 +
| ||Telavancin||+||+||||||+||+||+||+||+||+||+||+
 +
|-
 +
| ||[[Vancomycin]]||+||+||||||+||+/-||+||+||+||+||+||+
 
|}
 
|}
  

Revision as of 20:18, 25 March 2014

Gram Positives

' ' Gram Positive ' ' ' ' ' ' ' ' ' ' '
Category Antibiotic Strep. Group A, B, C, G Strep. Pneumoniae Viridans strep Strep. milleri Enterococcus faecalis Enterococcus faecium Staph. aureus (MSSA) Staph. aureus (MRSA) Staph. aureus (CA-MRSA) Staph. Epidermidis C. jeikeium L. monocytogenes
Penicillins Penicillin G + + +/- + + +/- 0 0 0 0 0 +
Penicillin V + + +/- + + +/- 0 0 0 0 0 0
Anti-Staphylocccal Penicillins Methicillin + + +/- + 0 0 + 0 0 + 0 0
Nafcillin/Oxacillin + + +/- + 0 0 + 0 0 + 0 0
Dicloxacillin + + +/- + 0 0 + 0 0 + 0 0
Amino-Penicillins AMP/Amox + + +/- + + + 0 0 0 0 0 +
Amox-Clav + + +/- + + + + 0 0 0 0
AMP-Sulb + + +/- + + + + 0 0 0 0 +
Anti-Pseudomonal Penicillins Ticarcillin + + +/- + +/- +/- 0 0 0 +/- 0 +
Ticar-Clav + + +/- + +/- +/- + 0 0 +/- 0
Pip-Tazo + + +/- + + +/- + 0 0 +
Carbapenems Doripenem + + + + +/- 0 + 0 0 + +
Ertapenem + + + + 0 0 + 0 0 + 0 +/-
Imipenem + + + + + +/- + 0 0 + 0 +
Meropenem + + + + +/- 0 + 0 0 + +
Aztreonam 0 0 0 0 0 0 0 0 0 0 0 0
Fluroquinolones Ciprofloxacin +/- +/- 0 0 ^^ 0 + 0 +/- + 0 +
Ofloxacin +/- +/- 0 0 ^^ 0 + 0 + 0 0
Levofloxacin + + + + + 0 + 0 +/- + +
Moxifloxacin + + + + + +/- + +/- +/- + +
Gemifloxacin + + + + + +/- + +/- +/- + +
Gatifloxacin + + + + + +/- + +/- +/- + +
1st G Cephalo Cefazolin + + + 0 + 0 0 +/- 0 0
2nd G Cephalo Cefotetan + + + 0 + 0 0 +/- 0 0
Cefoxitin + + + 0 + 0 0 +/- 0 0
Cefuroxime + + + 0 + 0 0 +/- 0 0
3rd/4th G Cephalo Cefotaxime + + + 0 + 0 0 +/- 0 0
Cefizoxime + + + 0 + 0 0 +/- 0 0
CefTRIAXone + + + 0 + 0 0 +/- 0 0
Ceftaroline + + + + + + + +
CefTAZidime + + +/- 0 +/- 0 0 +/- 0 0
Cefepime + + + 0 + 0 0 +/- 0
Oral 1st G Cephalo Cefadroxil + + + 0 + 0 0 +/- 0 0
Cephalexin + + + 0 + 0 0 +/- 0 0
Oral 2nd G Cephalo Cefaclor + + + 0 + 0 0 +/- 0 0
Cefproxil + + 0 0 + 0 0 +/- 0 0
Cefuroxime + + + 0 + 0 0 +/- 0 0
Oral 3rd G Cephalo Cefixime + + + 0 0 0 0 0 0 0
Ceftibuten + +/- 0 0 0 0 0 0 0 0
Cefpodox/ Cefdinir/ Cefditoren + + + 0 + 0 0 +/- 0
Aminoglycosides Gentamicin 0 0 S S + 0 +/- 0 S
Tobramycin 0 0 S 0 + 0 +/- 0 S
Amikacin 0 0 S 0 + 0 +/- 0 S
Chloramphenicol + + +/- +/- +/- 0 0 0 +
Clindamycin + + 0 0 + 0 +/- 0 0
Macrolides Erythromycin +/- + 0 0 +/- 0 +/- +/- 0 +
Azithromycin +/- + 0 0 + 0 +/- 0 0 +
Clarithromycin +/- + 0 0 + 0 +/- 0 0 +
Ketolide Telithromycin + +/- +/- 0 + 0 +/- 0 0 +
Tetracyclines Doxycycline +/- + 0 0 +/- +/- + 0 0 +
Minocycline + + 0 0 +/- +/- + 0 0 +
Glycylcycline Tigecycline + + + + + + + + + +
Sulfonamides TMP-SMX + + + 0 + + + +/- 0 +
Urinary Agents Nitrofurantoin + + + + + + + 0
Fosfomycin + +/-
Other Rifampin + + +/- 0 + + + + 0 +
Metronidazole 0 0 0 0 0 0 0 0 + 0
Quinupristin-dalfoppristin + + 0 + + + + + + +
Linezolid + + + + + + + + + +
Daptomycin + + + + + + + + 0 +/-
Colistimethate 0 0 0 0 0 0 0 0 0
Telavancin + + + + + + + + + +
Vancomycin + + + +/- + + + + + +

Gram Negatives

' ' N. gonorrhoeae
Penicillins Penicillin G 0
Penicillin V 0
Anti-Staphylocccal Penicillins Methicillin 0
Nafcillin/Oxacillin 0
Cloxacillin/Diclox. 0
Amino-Penicillins AMP/Amox 0
Amox-Clav +
AMP-Sulb +
Anti-Pseudomonal Penicillins Ticarcillin +
Ticar-Clav +
Pip-Tazo +
Carbapenems Piperacillin +
Doripenem +
Ertapenem +
Imipenem +
Meropenem +
Aztreonam +
Fluroquinolones Ciprofloxacin +*
Ofloxacin +*
Pefloxacin +*
Levofloxacin +*
Moxifloxacin +*
Gemifloxacin
Gatifloxacin +*
1st G Cephalosporins Cefazolin +
2nd G. Cephalosporins Cefotetan +/-
Cefoxitin +/-
Cefuroxime +/-
3rd/4th G. Cephalosporins Cefotaxime +/-
Cefizoxime +/-
CefTRIAXone +
Ceftobiprole +
Ceftaroline +
CefTAZidime +/-
Cefepime +
Oral 1st G. Cephalosporins Cefadroxil 0
Cephalexin 0
Oral 2nd G. Cephalosporins Cefaclor/Loracarbef +/-
Cefproxil +/-
Cefuroxime axetil +/-
Oral 3rd G. Cephalosporins Cefixime +
Ceftibuten +/-
Cefpodox/Cefdinir/Cefditoren +
Aminoglycosides Gentamicin 0
Tobramycin 0
Amikacin 0
Chloramphenicol +
Clindamycin 0
Macrolides Erythromycin +/-
Azithromycin +/-
Clarithromycin +/-
Ketolide Telithromycin +
Tetracyclines Doxycycline +/-
Minocycline +/-
Glycylcycline Tigecycline +
Glyco/Lipoclycopeptides Vancomycin 0
Teicoplanin 0
Telavancin 0
Fusidic Acid +
Trimethoprim 0
TMP-SMX +/-
Urinary Agents Nitrofurantoin +
Fosfomycin +
Other Rifampin +
Metronidazole 0
Quinupristin dalfoppristin +
Linezolid
Daptomycin 0
Colistimethate 0

Key

  • + usually effective clinically or >60% susceptible
  • +/- clinical trials lacking or 30-60% susceptible
  • 0 not effective clinically or <30% susceptible
  • blank data not available

See Also

Source

Sanford Guide to Antimicrobial Therapy 2010