Difference between revisions of "Viral hemorrhagic fevers"

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==Background==
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*Viral hemorrhagic fevers (VHFs) refer to a group of illnesses characterized by fever and hemorrhage
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*Caused by four distinct families of RNA viruses<ref name="Martines">Martines RB, Ng DL, Greer PW, Rollin PE, Zaki SR. Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses. J Pathol. 2015 Jan;235(2):153-74. doi: 10.1002/path.4456.</ref>
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**Filoviridae
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**Flaviviridae
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**Bunyaviridae
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**Arenaviridae
  
# meningococcemia, malaria, leptospirosis, rickettsia- all treatable with abx
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===VFHs Communicable by Person-to-Person Spread===
# also untreatable viruses- dengue, yellow fvr- but hem forms rarely seen in travelers
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*[[Ebola virus disease]]
# also consider Ebola and Lassa fever- public health hazard
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*[[Marburg virus disease]]
# h/o visit to rural area or contact with ill people in endemic area
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*[[Lassa fever]]
# usually 3 wk after exposure
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*[[Crimean-Congo hemorrhagic fever]]
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==Differential Diagnosis==
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{{Fever in Traveler DDX}}
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{{Bioterrorism agents}}
  
 
==See Also==
 
==See Also==
 
[[Travel Medicine]]
 
[[Travel Medicine]]
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==References==
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<references/>
  
 
[[Category:ID]]
 
[[Category:ID]]
[[Category:TropMed]]
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[[Category:Tropical Medicine]]

Latest revision as of 16:59, 22 March 2016

Background

  • Viral hemorrhagic fevers (VHFs) refer to a group of illnesses characterized by fever and hemorrhage
  • Caused by four distinct families of RNA viruses[1]
    • Filoviridae
    • Flaviviridae
    • Bunyaviridae
    • Arenaviridae

VFHs Communicable by Person-to-Person Spread

Differential Diagnosis

Fever in traveler

Bioterrorism Agents[2]

Category A

Category B

  • Ricin
  • Brucellosis
  • Epsilon toxin
  • Psittacosis
  • Q Fever
  • Staph enterotoxin B
  • Typhus
  • Glanders
  • Melioidosis
  • Food safety threats
  • Water safety threats
  • Viral encephalitis

Category C

See Also

Travel Medicine

References

  1. Martines RB, Ng DL, Greer PW, Rollin PE, Zaki SR. Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses. J Pathol. 2015 Jan;235(2):153-74. doi: 10.1002/path.4456.
  2. https://www.niaid.nih.gov/topics/biodefenserelated/biodefense/pages/cata.aspx Accessed 02/26/16