Diffuse alveolar hemorrhage

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Background

  • Diffuse Alveolar Hemorrhage (DAH) is a life-threatening condition
  • It is a subset of Pulmonary hemorrhage involving the microcirculation involving alveolar microvasculature
  • Most commonly the result of systemic vasculitis [1]

Clinical Features

Differential Diagnosis

Evaluation

  • Clinical suspicion with falling hematocrit
  • Radiographic imaging consistent with bilateral infiltration (CXR, CT) - can be patchy, focal or diffuse
  • Bronchoscopy with BAL showing sequentially increasing RBC counts

Management

Disposition

  • Typically requires upper level of care

See Also

External Links

Life in the Fast Lane: Diffuse Alveolar Hemorrhage

References

  1. Park M. Diffuse Alveolar Hemorrhage. Tuberc Resp Dis (Seoul) 2013. 74(4):151-162
  2. Lara A, Schwarz M. Diffuse Alveolar Hemorrhage. Chest 2010. 137(5):1164-1171
  3. Park M. Diffuse Alveolar Hemorrhage. Tuberc Resp Dis (Seoul) 2013. 74(4):151-162
  4. Wand O, et al. Inhaled Tranexamic Acid for Hemoptysis Treatment: A Randomized Controlled Trial. Chest. DOI: https://doi.org/10.1016/j.chest.2018.09.026