Docusate

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Administration

  • Type: stool softener; laxitive
  • Dosage Forms:
  • Routes of Administration: Oral, rectal
  • Common Trade Names: Colace

Adult Dosing

  • 50 to 200mg daily or in 2-4 divided doses

Pediatric Dosing

  • <3y: 10 to 40mg/day in 1-4 divided doses
  • 3-6y: 20 to 60mg/day in 1-4 divided doses
  • 6-12y: 40 to 120mg/day in 1-4 divided doses

Special Populations

Renal Dosing

  • Adult:
  • Pediatric:

Hepatic Dosing

  • Adult:
  • Pediatric:

Contraindications

  • Allergy to class/drug
  • Acute obstruction
  • Acute abdominal pain, vomiting
  • concurrent use of mineral oil

Adverse Reactions

Serious

  • Hepatotoxicity (Rare)

Common

Pharmacology

  • Half-life:
  • Metabolism:
  • Excretion:

Mechanism of Action

  • Draws water into stool

Comments

See Also

References