Portal vein thrombosis

Background

Inciting Causes

  • Abdominal sepsis
  • Abdominal surgery
  • Beh├žet's syndrome
  • Cirrhosis
  • Collagen vascular diseases (eg, lupus)
  • Compression or invasion of the portal vein by tumor (eg, pancreatic cancer)
  • Endoscopic sclerotherapy
  • Hepatocellular carcinoma
  • Inflammatory bowel disease
  • Inherited thrombophilias
  • Myeloproliferative syndromes
  • Omphalitis
  • Oral contraceptives
  • Pancreatic islet cell transplantation
  • Pancreatitis
  • Paroxysmal nocturnal hemoglobinuria
  • Pregnancy
  • Retroperitoneal fibrosis
  • Transjugular intrahepatic portosystemic shunt
  • Trauma

Clinical Features

Acute

  • Abdominal pain developing suddenly or progressing over a few days
  • May be clinically silent in a portion of patients and diagnosed during a CT exam for other reasons (e.g. acute pancreatitis)

Differential Diagnosis

Evaluation

  • Typically diagnosed on abdominal CT with contrast

Management

Disposition

See Also

External Links

References

Authors:

Ross Donaldson