Staphylococcus lugdunensis

Background

• Staphylococcus lugdunensis is a coagulase-negative staphylococcus with unusual pathogenicity resembling that of S. aureus
• A Gram Positive Bacteria
• Causes endocarditis, meningitis, and Skin and Soft Tissue Infections

Antibiotic susceptibility pattern of 540 Staphylococcus lugdunensis isolates tested with the disc diffusion method:

Antibiotic	No. (%) susceptible
Penicillin G	403 (74.6)
Gentamicin	538 (99.6)
Rifampicin	538 (99.6)
Cefoxitin	538 (99.6)
Fusidic acid	528 (97.8)
Trimethoprim/sulfamethoxazole	539 (99.8)
Norfloxacin	539 (99.8)
Clindamycin	494 (91.5)
Erythromycin	506 (93.7)

Antibiotic Sensitivities

Key

• S susceptible/sensitive (usually)
• I intermediate (variably susceptible/resistant)
• R resistant (or not effective clinically)
• S+ synergistic with cell wall antibiotics
• U sensitive for UTI only (non systemic infection)
• X1 no data
• X2 active in vitro, but not used clinically
• X3 active in vitro, but not clinically effective for Group A strep pharyngitis or infections due to E. faecalis
• X4 active in vitro, but not clinically effective for strep pneumonia

See Also

• Microbiology (Main)
• Staphylococcus Species