Template:Amiodarone adverse effects

Bradycardia
Hypotension with older solvent-based formulation. Uncommon with newer aqueous formulation.
Prolonged QT
Thyrotoxicosis^[1]
- Between 5-20% of patients treated with amiodarone have thyrotoxicosis (higher in areas of iodine deficiency)
Iodine-induced hyperthyroidism
- It is thought that the iodine load may unmask hyperthyroidism in patients with multinodular goiter and subclinical Graves’ disease
Drug-induced destructive thyroiditis
- More commonly, the cytotoxic effects of amiodarone destroy thyroid cells, resulting in a release of preformed hormone.
Amiodarone pulmonary toxicity
Hyperpigmentation rash