Template:Babesiosis Antibiotics

Each regimin is for 10 days duration and option 1 is often used for mild parasitemia <4% with option two for sever cases with >4% parasite load

Option 1

Atovaquone (750mg BID) and Azithromycin (500-1000mg on first day, 250-1000mg on subsequent days)

Option 2

Clindamycin

• 600 mg PO q8h x 7-10 days
• Alt: 300-600mg IV q6h x 7-10 days
  • First Dose: 300-600mg IV x 1
• Give with Quinine (650mg TID); use IV for severe infections

Pediatrics

• Clindamycin 20mg/kg/day for children and 25mg/kg/day for children for 7-10 days

Krause PJ, Lepore T, Sikand VK, Gadbaw J Jr, Burke G, Telford SR 3rd, et al. Atovaquone and azithromycin for the treatment of babesiosis. N Engl J Med. Nov 16 2000;343(20):1454-8.