Template:Otitis Externa Antibiotics

  1. Floxin otic: 5 drops in affected ear BID x 7 days[1]
    • Safe with perforations
  2. Cipro HC otic: 3 drops in affected ear BID x 7 days
    • Contains hydrocortisone to promote faster healing
    • Not safe with perforation
  3. CiproDex: 4 drops in affected ear BID x 7 days
  4. Cortisporin otic (neomycin/polymixin B/hydrocortisone)
    • 4 drops in ear TID-QID x 7days
    • Use suspension (NOT solution) if possiblity of perforation
    • Animal studies suggest possible toxicity from the neomycin although rigorous data is lacking[2]
  5. Clinical Practice Guideline: Acute Otitis Externa Executive Summary. Otolaryngology -- Head and Neck Surgery 2014 150: 161 DOI: 10.1177/0194599813517659 PDF
  6. Wright, C. et al. Ototoxicity of neomycin and polymyxin B following middle ear application in the chinchilla and baboon. Am J Otol. 1987 Nov;8(6):495-9.