EBQ:Sodium Bicarbonate use in DKA: Difference between revisions
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Should we use Sodium Bicarbonate in Acidosis ? | Should we use Sodium Bicarbonate in Acidosis ? | ||
==Background== | ==Background== | ||
Sodium bicarbonate is a solution which help alkalanizing the blood by binding the H+ and converting it to water and Co<sub>2</sub>. Many Physicians use it to treat Acidosis, but based on what ? Is there any evidence ? | Sodium bicarbonate is a solution which help alkalanizing the blood by binding the H<sup>+</sup> and converting it to water and Co<sub>2</sub>. Many Physicians use it to treat Acidosis, but based on what ? Is there any evidence ? | ||
==Pro Argument== | ==Pro Argument== | ||
Revision as of 17:17, 14 April 2014
Clinical Question
Should we use Sodium Bicarbonate in Acidosis ?
Background
Sodium bicarbonate is a solution which help alkalanizing the blood by binding the H+ and converting it to water and Co2. Many Physicians use it to treat Acidosis, but based on what ? Is there any evidence ?
Pro Argument
Trial 1
Trial 2
Trial 3
Con Argument
Trial 1
21 patients underwent RCT
- 10 patients (PH 6.9-7.14)received NaHco3
- 11 patients in the control group
Results: No differences in Glucose level, bicarb level nor PH [1]
Trial 2
Trial 3
- ↑ Ann Intern Med. 1986 Dec;105(6):836-40
http://saudiemergencymedicine.com/should-you-use-sodium-bicarbonate-in-acidosis-stop-for-a-minute/