EBQ:Sodium Bicarbonate use in DKA: Difference between revisions

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Revision as of 20:08, 14 April 2014

Clinical Question

Should Sodium Bicarbonate be used to treat metabolic acidosis?

Background

Sodium bicarbonate is a solution which help alkalanizing the blood by binding the H+ and converting it to water and Co2. Many Physicians use it to treat Acidosis, but based on what ? Is there any evidence ?

Pro Argument

Trial 1

Trial 2

Trial 3

Con Argument

Trial 1

21 patients underwent RCT

  • 10 patients (PH 6.9-7.14)received NaHco3
  • 11 patients in the control group

Results: No differences in Glucose level, bicarb level nor PH [1]

Trial 2

Trial 3

Sources

  1. Ann Intern Med. 1986 Dec;105(6):836-40

http://saudiemergencymedicine.com/should-you-use-sodium-bicarbonate-in-acidosis-stop-for-a-minute/