EBQ:Sodium Bicarbonate use in DKA

Clinical Question

Should we use Sodium Bicarbonate in Acidosis ?

Background

Sodium bicarbonate is a solution which help alkalanizing the blood by binding the H+ and converting it to water and Co₂. Many Physicians use it to treat Acidosis, but based on what ? Is there any evidence ?

Con Argument

Trial 1

21 patients underwent RCT

• 10 patients (PH 6.9-7.14)received NaHco3
• 11 patients in the control group

Results: No differences in Glucose level, bicarb level nor PH

Trial 3

http://saudiemergencymedicine.com/should-you-use-sodium-bicarbonate-in-acidosis-stop-for-a-minute/