EBQ:Perry Subarachnoid Haemorrhage Study

incomplete Journal Club Article
Perry JJ et al. "High risk clinical characteristics for subarachnoid haemorrhage in patients with acute headache: prospective cohort study". BMJ. 2010. 28(341):c5204.
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Clinical Question

What is the sensitivity of non-contrast head CT for detecting spontaneous subarachnoid hemorrhage (SAH), when performed on a third-generation CT scanner within 6 hours of headache onset?

Conclusion

Major Points

Inclusion Criteria

  • >15 years old
  • Acute headache reaching peak intensity within one hour
  • Normal neurologic exam
  • CT ordered by the treating physician to rule out SAH

Exclusion Criteria

  • Focal neurologic deficits
  • Papilledema
  • History of SAH
  • History aneurysm
  • Previous VP shunt
  • Brain neoplasm
  • Onset of headache >14 days ago
  • Recurrent headache (≥3 similar)
  • Transfer with confirmed diagnosis of SAH

Interventions

Outcome

Primary Outcomes

Secondary Outcomes

Subgroup analysis

Criticisms

Funding

Sources