Sinusitis: Difference between revisions

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<center>More common</center>
<center>More common</center>
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==Basic Management==
< 10 days symptomatic treatment b/c most likely viral
* Analgesia
* Mechanical irrigation with buffered, hypertonic saline
* Topical glucocorticoids
* Topical decongestants (e.g., oxymetazoline for no more than three days)
* Antihistamines
* Mucolytics
> 10 days or if pt gets better and then worse again (“double sickening”)
* Mild bacterial sinusitis when pain is mild and temperature < 38.3˚C
** Another seven days of observation
* Severe bacterial sinusitis when pain is moderate-severe or temperature ≥38.3˚C
** Consider antibiotics
* If the patient is immunocompromised, has an underlying or complicating condition, or patient fails observation, antibiotics are indicated
Antibiotics
* Choice of antibiotic depends on recent antibiotic therapy (past 4-6 weeks).
** Amoxicillin (500mg PO TID for 10 days)
** TMP-SMX
** Erythromycin
** <span style="display: none; line-height: 0"></span>Azithromycin
** <span style="display: none; line-height: 0"><span style="display: none; line-height: 0"><span style="display: none; line-height: 0"></span></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span></span>Cefpodoxime<span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"><span style="display: none; line-height: 0"></span></span>
* <span style="display: none; line-height: 0"><span style="display: none; line-height: 0"><span style="display: none; line-height: 0"></span></span></span>Cefdinir<span style="display: none; line-height: 0"><span style="display: none; line-height: 0"></span></span>
* <span style="display: none; line-height: 0"><span style="display: none; line-height: 0"></span></span>Cefuroxime<span style="display: none; line-height: 0"><span style="display: none; line-height: 0"><span style="display: none; line-height: 0"></span></span></span>
** <span style="display: none; line-height: 0"></span>If initial antibiotic failure occurs consider further workup (e.g. CT) and/or further tx with either amoxicillin-clavulanate or respiratory fluoroquinolone
** Nosocomial acute bacterial rhinosinusitis can occur (e.g., after prolonged nasotracheal intubation) and often is associated with gram-negatives; remove foreign bodies and use culture-directed antibiotic therapy
** Immunocompromised patients at risk for acute fulminant fungal rhinosinusitis==Source==DeBonis, Kaji<span style="display: none; line-height: 0"></span>,<span style="display: none; line-height: 0"></span> <span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span>U<span style="display: none; line-height: 0"></span>p<span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span>T<span style="display: none; line-height: 0"></span>o<span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span><span style="display: none; line-height: 0"></span>D<span style="display: none; line-height: 0"></span>a<span style="display: none; line-height: 0"></span>t<span style="display: none; line-height: 0"></span>e "Rhinosinusitis"<div id="wikiedit" style="display: none"><div id="editor-panel" class="box">=Sinusitis[/rename.php?renamepage=Sinusitis  ]={| id="edit-panel" style="table-layout: fixed; width: 100%"
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== Basic Management ==
== Basic Management ==
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*If the patient is immunocompromised, has an underlying or complicating condition, or patient fails observation, antibiotics are indicated
*If the patient is immunocompromised, has an underlying or complicating condition, or patient fails observation, antibiotics are indicated


<br/>Antibiotics
===Antibiotics===


*Choice of antibiotic depends on recent antibiotic therapy (past 4-6 weeks).
*Choice of antibiotic depends on recent antibiotic therapy (past 4-6 weeks).
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*Azithromycin
*Azithromycin
*Cefpodoxime
*Cefpodoxime
* Cefdinir * Cefuroxime
* Cefdinir * Cefuroxime
 


 
*If initial antibiotic failure occurs consider further workup (e.g. CT) and/or further tx with either amoxicillin-clavulanate or respiratory fluoroquinolone
*If initial antibiotic failure occurs consider further workup (e.g. CT) and/or further tx with either amoxicillin-clavulanate or respiratory fluoroquinolone
*Nosocomial acute bacterial rhinosinusitis can occur (e.g., after prolonged nasotracheal intubation) and often is associated with gram-negatives; remove foreign bodies and use culture-directed antibiotic therapy
*Nosocomial acute bacterial rhinosinusitis can occur (e.g., after prolonged nasotracheal intubation) and often is associated with gram-negatives; remove foreign bodies and use culture-directed antibiotic therapy



Revision as of 07:40, 12 March 2011

Background

Rhinosinusitis - Inflammation of the lining of the paranasal sinuses

Acute (< 4 weeks)

  • Acute viral
  • Acute bacterial (0.5-2% of cases)

Subacute (4-12 weeks)

Chronic (>12 weeks)

Other causes

  • Fungal infections
  • Allergies

Diagonsis

Classic History & Physical

Feature
Viral
Bacterial

Duration (symptoms)

<10days
Usually >10 days OR worsening symptoms within 10 days after initial improvement

Color change (nasal discharge)

+/−
+++, quality usually yellow-green and thick

Maxillary dental pain

+++, often unilateral and associated with a particular sinus

Postnasal drip

More common

Fever, cough, fatigue

More common

Hyposmia/anosmia

More common

Basic Management

< 10 days symptomatic treatment b/c most likely viral

  • Analgesia
  • Mechanical irrigation with buffered, hypertonic saline
  • Topical glucocorticoids
  • Topical decongestants (e.g., oxymetazoline for no more than three days)
  • Antihistamines
  • Mucolytics


> 10 days or if pt gets better and then worse again (“double sickening”)

  • Mild bacterial sinusitis when pain is mild and temperature < 38.3˚C
  • Another seven days of observation
  • Severe bacterial sinusitis when pain is moderate-severe or temperature ≥38.3˚C
  • Consider antibiotics
  • If the patient is immunocompromised, has an underlying or complicating condition, or patient fails observation, antibiotics are indicated

Antibiotics

  • Choice of antibiotic depends on recent antibiotic therapy (past 4-6 weeks).
  • Amoxicillin (500mg PO TID for 10 days)
  • TMP-SMX
  • Erythromycin
  • Azithromycin
  • Cefpodoxime

* Cefdinir * Cefuroxime 

  • If initial antibiotic failure occurs consider further workup (e.g. CT) and/or further tx with either amoxicillin-clavulanate or respiratory fluoroquinolone
  • Nosocomial acute bacterial rhinosinusitis can occur (e.g., after prolonged nasotracheal intubation) and often is associated with gram-negatives; remove foreign bodies and use culture-directed antibiotic therapy


  • Immunocompromised patients at risk for acute fulminant fungal rhinosinusitis


Source

DeBonis, Kaji, UpToDate "Rhinosinusitis"