SGLT-2 Inhibitor: Difference between revisions

(Created page with "==Administration== *Type: Diabetes medication *Canagliflozin (Invokana), Dapagliflozin (Farxiga), empagliflozin (Jardiance) are FDA approved for use in type 2 diabetes ==...")
 
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===Common===
===Common===
*UTI
*[[UTI]]
*Genital candidiasis
*Genital candidiasis
*Weight loss
*Weight loss

Revision as of 03:19, 18 April 2017

Administration

  • Type: Diabetes medication
  • Canagliflozin (Invokana), Dapagliflozin (Farxiga), empagliflozin (Jardiance) are FDA approved for use in type 2 diabetes

Contraindications

  • Allergy to class/drug

Adverse Reactions

Serious

  • Euglycemic DKA[1]

Common

  • UTI
  • Genital candidiasis
  • Weight loss
  • Dehydration/Orthostasis

Mechanism of Action

  • Inhibit sodium-glucose cotransporter 2, decreasing glucose reabsorption in the proximal tubule

References