Chlorate toxicity: Difference between revisions
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*Based on clinical history and presence of methemoglobinemia | *Based on clinical history and presence of methemoglobinemia | ||
*No specific levels are available | *No specific levels are available | ||
Revision as of 23:10, 20 August 2017
Background
- Potassium Chlorate, Barium Chlorate, and Sodium Chlorate are still in use today
- Fireworks, match heads, and weed killers
Mechanism of Toxicity
- Oxidizers and attackers of sulfhydryl groups
- Cause methemoglobin formation
Clinical Presentation
Differential Diagnosis
Evaluation
- Based on clinical history and presence of methemoglobinemia
- No specific levels are available
Management
- Activated charcoal IS recommended
- Methylene blue for methemoglobinemia (1-2 mg/kg of 1% solution)
- Sodium thiosulfate IV may inactivate chlorate ions (anecdotal)
- Hemodialysis
- Supportive Care
Disposition
External Links
References
Olson, K. Poisoning and Drug Overdose, 1999.