Inhalation injury: Difference between revisions

(Text replacement - "==Diagnosis==" to "==Evaluation==")
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==Background==
==Background==
* Inhalational injury a concern with history of being trapped in enclosed space for some time with toxic gases / fumes


==Clinical Features==
==Clinical Features==
* Initial signs/symptoms - coughing, wheezing, dyspnea, irritated mucous members (runny eyes/nose), chest pain, hypoxia
* Specific features dependent on type of exposure
===Inert Gases===
* Inert gases (carbon dioxise, fuel gases) displace air and oxygen producing asphyxia
* Present with severe hypoxia
===Irritant Gases===
* Irritant gases (ammonia, formaldehyde, chlorine, nitrogen dioxide) when dissolved in water lining respiratory tract produce a chemical burn and inflammatory response
* More soluble the gas produces more upper airway burns/irritation symptoms
* Less soluble gases produce more pulmonary injury and respiratory distress
===Systemic Toxins===
* Includes carbon monoxide, hydrogen cyanide, hydrogen sulfide
* Interfere with delivery of oxygen for use in cellular energy production
* Liver, kidney, brain, lung and other organ damage
===Allergic===
* Inhaled gases, particles, aerosols
* Produce bronchospasms and edema similar to asthma
===Smoke Inhalation / Thermal ===
* Most fatalities from burn injuries are attributed to smoke inhalation
* Soot in posterior pharynx, singed nasal hair
* Hyperacute - severe wheezing, bronchoconstriction, significant hypoxemia
* Acute pulmonary edema - onset at 48-72 hours post injury in a previously asymptomatic patient
* Bronchopneumonia often at 10 days post-inury


==Differential Diagnosis==
==Differential Diagnosis==
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==Evaluation==
==Evaluation==
*Look for evidence of exposure
** Estimated time of exposure
** Open or enclosed space
** Associated events such as fire, blast, etc.?
** Is the exposure known?
** Material on patient? Does patient smell of chemical?
: Examples - smoke inhalation from burning building, leak of a solvent, chemical fumes
* Physical examination with focus on airway and pulmonary system
* Observe of evidence of airway compromise or respiratory distress


==Management==
==Management==
===General===
* Separate patient from fumes/toxic agent
* Decontaminate if not done on scene
* Secure airway if necessary and ventilate
* Oxygen at 6-12 liters per minute via mask
* Chest x-ray, pulse oximetry, arterial blood gases
* Consider carboxyhemoglobin level or cyanide level if any suspicion based on history
* Observe for respiratory distress and airway compromise
===Inert Gases===
* Remove victim from the gas
* Fresh air or oxygen
* Observe for sequelae  from hypoxia (myocardial infarction, cerebral injury)
===Allergic===
* Aerosolized bronchodilators
* Corticosteroids in patients with history of reactive airway disease
===Smoke Inhalation / Thermals===
* Ensure adequate oxygenation, ventilation, pulmonary toilet and fluid resuscitation


==Disposition==
==Disposition==
* Respiratory distress or airway compromise will need admission
* Observe for 1-4 hours if no signs or symptoms of inhalation injury develop or if all resolved within 1 hour consider discharging patient home with instructions for return for re-evaluation next day or sooner if pulmonary and/or airway symptoms develop


==See Also==
==See Also==
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==References==
==References==
<references/>
<references/>
[[Category:Environmental]] [[Category:Toxicology]]

Revision as of 05:04, 3 February 2018

Background

  • Inhalational injury a concern with history of being trapped in enclosed space for some time with toxic gases / fumes

Clinical Features

  • Initial signs/symptoms - coughing, wheezing, dyspnea, irritated mucous members (runny eyes/nose), chest pain, hypoxia
  • Specific features dependent on type of exposure

Inert Gases

  • Inert gases (carbon dioxise, fuel gases) displace air and oxygen producing asphyxia
  • Present with severe hypoxia

Irritant Gases

  • Irritant gases (ammonia, formaldehyde, chlorine, nitrogen dioxide) when dissolved in water lining respiratory tract produce a chemical burn and inflammatory response
  • More soluble the gas produces more upper airway burns/irritation symptoms
  • Less soluble gases produce more pulmonary injury and respiratory distress

Systemic Toxins

  • Includes carbon monoxide, hydrogen cyanide, hydrogen sulfide
  • Interfere with delivery of oxygen for use in cellular energy production
  • Liver, kidney, brain, lung and other organ damage

Allergic

  • Inhaled gases, particles, aerosols
  • Produce bronchospasms and edema similar to asthma

Smoke Inhalation / Thermal

  • Most fatalities from burn injuries are attributed to smoke inhalation
  • Soot in posterior pharynx, singed nasal hair
  • Hyperacute - severe wheezing, bronchoconstriction, significant hypoxemia
  • Acute pulmonary edema - onset at 48-72 hours post injury in a previously asymptomatic patient
  • Bronchopneumonia often at 10 days post-inury

Differential Diagnosis

Inhalation injury

Unintentional
Terrorism

Evaluation

  • Look for evidence of exposure
    • Estimated time of exposure
    • Open or enclosed space
    • Associated events such as fire, blast, etc.?
    • Is the exposure known?
    • Material on patient? Does patient smell of chemical?
Examples - smoke inhalation from burning building, leak of a solvent, chemical fumes
  • Physical examination with focus on airway and pulmonary system
  • Observe of evidence of airway compromise or respiratory distress

Management

General

  • Separate patient from fumes/toxic agent
  • Decontaminate if not done on scene
  • Secure airway if necessary and ventilate
  • Oxygen at 6-12 liters per minute via mask
  • Chest x-ray, pulse oximetry, arterial blood gases
  • Consider carboxyhemoglobin level or cyanide level if any suspicion based on history
  • Observe for respiratory distress and airway compromise

Inert Gases

  • Remove victim from the gas
  • Fresh air or oxygen
  • Observe for sequelae from hypoxia (myocardial infarction, cerebral injury)

Allergic

  • Aerosolized bronchodilators
  • Corticosteroids in patients with history of reactive airway disease

Smoke Inhalation / Thermals

  • Ensure adequate oxygenation, ventilation, pulmonary toilet and fluid resuscitation

Disposition

  • Respiratory distress or airway compromise will need admission
  • Observe for 1-4 hours if no signs or symptoms of inhalation injury develop or if all resolved within 1 hour consider discharging patient home with instructions for return for re-evaluation next day or sooner if pulmonary and/or airway symptoms develop

See Also

External Links

Video

{{#widget:YouTube|id=CB10airH5Sg}}

References