Pantoprazole: Difference between revisions
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Revision as of 04:43, 2 May 2019
General
- Type: Proton-pump inhibitor
- Dosage Forms:
- Common Trade Names: Protonix, Somac, Forppi, Pantoloc, Pantozol, Pantomed, Zurcal, Zentro, Pan, Controloc, Tecta
Adult Dosing
Upper gastrointestinal bleeding
- 80mg x 1; then 8mg/hr
Pediatric Dosing
Special Populations[1]
- Pregnancy Rating:
- Lactation:
- Pantoprazole is present in breast milk
- Renal Dosing
- Adult
- No adjustment necessary
- Pediatric
- Not defined
- Adult
- Hepatic Dosing
- Adult
- No adjustment necessary
- Pediatric
- Not defined
- Adult
Contraindications
- Allergy to class/drug
Adverse Reactions
Serious
- anaphylaxis
- SJS/TEN
- Renal impairment
- pancreatitis
- hepatic impairment
Common
- Headache
- abdominal pain
- nausea/vomiting/diarrhea
- AST/ALT elevation
Pharmacology
- Half-life: 1 hour
- Metabolism: Hepatic - CYP450
- Excretion: Urine/Feces
- Mechanism of Action: inhibits gastric parietal cell H+/K+ ATPase
See Also
References
- ↑ Pantoprazole: Drug information. UpToDate. www.uptodate.com. Accessed April 2, 2019.