Alpha blockers: Difference between revisions
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==Uses== | ==Uses== | ||
*[[hypertension]] | *[[hypertension]] | ||
*[[ | *[[Raynaud’s disease]] | ||
*[[scleroderma]] | *[[scleroderma]] | ||
*[[generalized anxiety disorder]] | *[[generalized anxiety disorder]] | ||
Latest revision as of 14:28, 19 October 2019
Background
- Also known as α-blockers
- α1-blockers act on α1-adrenoceptors
- α2-blockers act on α2-adrenoceptors
- Act as neutral antagonists or inverse agonists of α-adrenergic receptors (α-adrenoceptors)
Medications
Non-selective
- Phenoxybenzamine
- Phentolamine
- Tolazoline
- Trazodone
- Typical and atypical antipsychotics
Selective α1
Selective α2
Mixed
- The agents carvedilol and labetalol are both α- and β-blockers.
Uses
- hypertension
- Raynaud’s disease
- scleroderma
- generalized anxiety disorder
- panic disorder
- posttraumatic stress disorder
- benign prostatic hyperplasia
