Cephalosporins: Difference between revisions

Latest revision as of 01:29, 21 February 2021

1st Generation

Skin and soft tissue infections (why is agent of choice before generalized symptoms)
Cross-reactivity of PCN allergy <10%

2nd Generation

Intestinal anaerobes (why is agent of choice for colorectal sx)
Largely displaced by 3rd gen agents

3rd Generation

Drug of choice for serious infections due to:
- Klebsiella
- Enterobacter
- Proteus
- Haemophilus
Gonorrhea
Lyme Disease
Meningitis (+ vanc and ampicillin)
Pseudomonas meningitis (+ AG)

4th Generation

Resistant, nosocomial infections

References

Goodman & Gilman's Pharmacology

Authors:

@@ Line 1: / Line 1: @@
 ==1st Generation==
-* Cefazolin, [[Cephalexin]]
+*Skin and soft tissue infections (why is agent of choice before generalized symptoms)
-** Skin and soft tissue infections (why is agent of choice before gen sx)
+*[[EBQ:Cephalosporin Cross-reactivity|Cross-reactivity of PCN]] allergy <10%
-* [[Ceftriaxone_Cross-reactivity|Cross-reactivity of PCN]] allergy <10%
 ==2nd Generation==
-* Cefuroxime
+*Intestinal [[anaerobes]] (why is agent of choice for colorectal sx)
-** Intestinal anaerobes (why is agent of choice for colorectal sx)
+*Largely displaced by 3rd gen agents
-** Largely displaced by 3rd gen agents
 ==3rd Generation==
-*[[Ceftriaxone]], Ceftazidime, Cefixime
+*Drug of choice for serious infections due to:
-** Drug of choice for serious infections due to:
+**[[Klebsiella]]
-*** Klebsiella
+**[[Enterobacter]]
-*** Enterobacter
+**Proteus
-*** Proteus
+**[[Haemophilus]]
-*** Haemophilus
+*[[Gonorrhea]]
-** [[Gonorrhea]]
+*[[Lyme Disease]]
-** [[Lyme Disease]]
+*[[Meningitis]] (+ [[vanc]] and [[ampicillin]])
-** [[Meningitis]] (+ vanc and ampicillin)
+*[[Pseudomonas]] meningitis (+ AG)
-** Pseudomonas meningitis (+ AG)
 ==4th Generation==
-* Cefepime
+*Resistant, nosocomial infections
-** Resistant, nosocomial infections
-{{Template:Clinically Utilized Antibiotics}}
+{{Clinically Utilized Antibiotics}}
 ==See Also==
@@ Line 28: / Line 27: @@
 *[[Cephalosporin Cross-reactivity]]
-==Source==
+==References==
+<references/>
 Goodman & Gilman's Pharmacology
-[[Category:Drugs]]
+[[Category:Pharmacology]]
 [[Category:ID]]