Template:Jaundice DDX: Difference between revisions
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===[[Jaundice]]=== | ===[[Jaundice]]=== | ||
[[File:Classification of Hyperbilirubinemia.jpeg|thumb|Differential diagnosis of hyperbilirubinemia.]] | |||
====Indirect Hyperbilirubinemia==== | ====Indirect Hyperbilirubinemia==== | ||
*Hemolytic | *Hemolytic | ||
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**Pancreatic head | **Pancreatic head | ||
**Gallbladder | **Gallbladder | ||
**Primary liver (e.g. [[hepatocellular carcinoma]] | **Primary liver (e.g. [[hepatocellular carcinoma]]) | ||
**Metastatic | **Metastatic | ||
*Obstructing [[AAA]] | *Obstructing [[AAA]] | ||
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====Pregnancy Related==== | ====Pregnancy Related==== | ||
*[[HELLP | *[[HELLP syndrome]] | ||
*[[Acute fatty liver of pregnancy]] | *[[Acute fatty liver of pregnancy]] | ||
*[[Hyperemesis gravidarum]] | *[[Hyperemesis gravidarum]] | ||
Latest revision as of 13:33, 25 November 2021
Jaundice
Indirect Hyperbilirubinemia
- Hemolytic
- G6PD
- Drug related
- Autoimmune hemolytic anemia
- Hematoma resorption
- Ineffective erythropoiesis
- Gilbert's
Direct (Conjugated) Hyperbilirubinemia
- Choledocholithiasis
- Cholecystitis
- Ascending cholangitis
- AIDS cholangiopathy
- Stricture
- Neoplasm
- Pancreatic head
- Gallbladder
- Primary liver (e.g. hepatocellular carcinoma)
- Metastatic
- Obstructing AAA
Hepatocellular damage
Patient will have severely elevated AST/ALT with often normal Alkaline Phosphatase
- Viral hepatitis
- Fulminant hepatic failure
- alcoholic hepatitis
- Ischemic hepatitis
- Toxins
- Isoniazid
- Phenytoin
- acetaminophen
- Ritonavir
- Halothane
- Sulfonamide
- Autoimmune hepatitis
- Primary biliary cirrhosis
- HELLP Syndrome
- Congestive Hepatopathy
Pregnancy Related
Transplant Related
Pediatric Related
- Inborn error of metabolism
- Neonatal jaundice (physiologic)
Additional Differential Diagnosis
- Reye syndrome
- TPN
- Heatstroke
- Budd-Chiari (with acute ascites)
- Wilson's disease
- Sarcoidosis
- Amyloidosis
Masqueraders
Only bilirubin stains the sclera
- Carotenemia
- Quinacrine ingestion
- Dinitrophenol, teryl (explosive chemicals)