Template:Otitis Externa Antibiotics: Difference between revisions
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#{{AntibioticDose|drug=Ofloxacin|dose=5 drops in affected ear BID x 7 days|context=Topical}} (Floxin otic)<ref name="CPGENT2014">Clinical Practice Guideline: Acute Otitis Externa Executive Summary. Otolaryngology -- Head and Neck Surgery 2014 150: 161 DOI: 10.1177/0194599813517659 [http://www.aepap.org/sites/default/files/otitis_externa_guia2014-rosenfeld-161-8_0.pdf PDF]</ref> | #{{AntibioticDose|disease=Otitis externa|drug=Ofloxacin|dose=5 drops in affected ear BID x 7 days|context=Topical}} (Floxin otic)<ref name="CPGENT2014">Clinical Practice Guideline: Acute Otitis Externa Executive Summary. Otolaryngology -- Head and Neck Surgery 2014 150: 161 DOI: 10.1177/0194599813517659 [http://www.aepap.org/sites/default/files/otitis_externa_guia2014-rosenfeld-161-8_0.pdf PDF]</ref> | ||
#*Safe with perforations | #*Safe with perforations | ||
#{{AntibioticDose|drug=Ciprofloxacin|dose=3 drops in affected ear BID x 7 days|context=Topical (Cipro HC)|display=Ciprofloxacin-hydrocortisone}} | #{{AntibioticDose|disease=Otitis externa|drug=Ciprofloxacin|dose=3 drops in affected ear BID x 7 days|context=Topical (Cipro HC)|display=Ciprofloxacin-hydrocortisone}} | ||
#*Contains hydrocortisone to promote faster healing | #*Contains hydrocortisone to promote faster healing | ||
#*Not recommended for perforation since non-sterile preparation | #*Not recommended for perforation since non-sterile preparation | ||
#{{AntibioticDose|drug=Ciprofloxacin|dose=4 drops in affected ear BID x 7 days|context=Topical (Ciprodex)|display=Ciprofloxacin-dexamethasone}} | #{{AntibioticDose|disease=Otitis externa|drug=Ciprofloxacin|dose=4 drops in affected ear BID x 7 days|context=Topical (Ciprodex)|display=Ciprofloxacin-dexamethasone}} | ||
#*Similar to Cipro HC but safe for perforations | #*Similar to Cipro HC but safe for perforations | ||
#*Often more expensive | #*Often more expensive | ||
#{{AntibioticDose|drug=Cortisporin otic|dose=4 drops in ear TID-QID x 7days|context=Topical}} (neomycin/polymixin B/hydrocortisone) | #{{AntibioticDose|disease=Otitis externa|drug=Cortisporin otic|dose=4 drops in ear TID-QID x 7days|context=Topical}} (neomycin/polymixin B/hydrocortisone) | ||
#*Use '''suspension''' (NOT solution) if possibility of perforation | #*Use '''suspension''' (NOT solution) if possibility of perforation | ||
#*Animal studies suggest possible toxicity from the neomycin although rigorous data is lacking<ref>Wright, C. et al. Ototoxicity of neomycin and polymyxin B following middle ear application in the chinchilla and baboon. Am J Otol. 1987 Nov;8(6):495-9.</ref> | #*Animal studies suggest possible toxicity from the neomycin although rigorous data is lacking<ref>Wright, C. et al. Ototoxicity of neomycin and polymyxin B following middle ear application in the chinchilla and baboon. Am J Otol. 1987 Nov;8(6):495-9.</ref> | ||
'''Pediatric:''' | |||
''Same topical regimens apply to children'' | |||
#{{AntibioticDose|disease=Otitis externa|drug=Ofloxacin|dose=5 drops (>12yr) or 3 drops (<12yr) in affected ear BID x 7 days|context=Pediatric Topical|population=Pediatric}} | |||
#{{AntibioticDose|disease=Otitis externa|drug=Ciprofloxacin|dose=3-4 drops in affected ear BID x 7 days|context=Pediatric Topical|population=Pediatric}} (with dexamethasone or hydrocortisone) | |||
Latest revision as of 13:08, 20 March 2026
- Ofloxacin 5 drops in affected ear BID x 7 days (Floxin otic)[1]
- Safe with perforations
- Ciprofloxacin-hydrocortisone 3 drops in affected ear BID x 7 days
- Contains hydrocortisone to promote faster healing
- Not recommended for perforation since non-sterile preparation
- Ciprofloxacin-dexamethasone 4 drops in affected ear BID x 7 days
- Similar to Cipro HC but safe for perforations
- Often more expensive
- Cortisporin otic 4 drops in ear TID-QID x 7days (neomycin/polymixin B/hydrocortisone)
- Use suspension (NOT solution) if possibility of perforation
- Animal studies suggest possible toxicity from the neomycin although rigorous data is lacking[2]
Pediatric: Same topical regimens apply to children
- Ofloxacin 5 drops (>12yr) or 3 drops (<12yr) in affected ear BID x 7 days
- Ciprofloxacin 3-4 drops in affected ear BID x 7 days (with dexamethasone or hydrocortisone)
- ↑ Clinical Practice Guideline: Acute Otitis Externa Executive Summary. Otolaryngology -- Head and Neck Surgery 2014 150: 161 DOI: 10.1177/0194599813517659 PDF
- ↑ Wright, C. et al. Ototoxicity of neomycin and polymyxin B following middle ear application in the chinchilla and baboon. Am J Otol. 1987 Nov;8(6):495-9.