Template:Epidural Abscess Treatment: Difference between revisions
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*Target [[Staphylococcus_Species|Staph]], [[Strep_Species|Strep]], and [[Gram_Negatives|Gram-negative bacilli]]<ref>Rigamonti D. et al. Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. Surg Neurol 1999; 52:189-96</ref> | |||
*Target [[Staphylococcus_Species| | *{{AntibioticDose|disease=Epidural abscess (spinal)|drug=Vancomycin|dose=15-20mg/kg BID|context=Empiric}} + {{AntibioticDose|disease=Epidural abscess (spinal)|drug=Metronidazole|dose=500mg (7.5mg/kg) q6 hrs|context=Empiric|link=no}} + ([[Cefotaxime]] or {{AntibioticDose|disease=Epidural abscess (spinal)|drug=Ceftriaxone|dose=standard dosing|context=Empiric|link=no}} or [[Ceftazidime]]) | ||
* | |||
**[[Ceftazidime]] is preferred if [[pseudomonas]] is considered likely | **[[Ceftazidime]] is preferred if [[pseudomonas]] is considered likely | ||
**Can substitute [[Nafcillin]] or [[Oxacillin]] for [[Vancomycin]] if not [[MRSA]] | **Can substitute [[Nafcillin]] or [[Oxacillin]] for [[Vancomycin]] if not [[MRSA]] | ||
''Treat for 6-8 weeks'' | ''Treat for 6-8 weeks'' | ||
====Pediatric==== | |||
*{{AntibioticDose|disease=Epidural abscess (spinal)|drug=Vancomycin|dose=15mg/kg IV q6hrs|context=Pediatric Empiric|population=Pediatric}} + {{AntibioticDose|disease=Epidural abscess (spinal)|drug=Ceftriaxone|dose=50-75mg/kg IV daily (max 2g)|context=Pediatric Empiric|population=Pediatric}} + {{AntibioticDose|disease=Epidural abscess (spinal)|drug=Metronidazole|dose=7.5mg/kg IV q6hrs (max 500mg)|context=Pediatric Empiric|population=Pediatric}} | |||
*Treat for 6-8 weeks | |||
Latest revision as of 13:21, 20 March 2026
- Target Staph, Strep, and Gram-negative bacilli[1]
- Vancomycin 15-20mg/kg BID + 500mg (7.5mg/kg) q6 hrs + (Cefotaxime or standard dosing or Ceftazidime)
- Ceftazidime is preferred if pseudomonas is considered likely
- Can substitute Nafcillin or Oxacillin for Vancomycin if not MRSA
Treat for 6-8 weeks
Pediatric
- Vancomycin 15mg/kg IV q6hrs + Ceftriaxone 50-75mg/kg IV daily (max 2g) + Metronidazole 7.5mg/kg IV q6hrs (max 500mg)
- Treat for 6-8 weeks
- ↑ Rigamonti D. et al. Spinal epidural abscess: contemporary trends in etiology, evaluation, and management. Surg Neurol 1999; 52:189-96